Richard Lafayette
Publication Details
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Anaritide in acute tubular necrosis. Auriculin Anaritide Acute Renal Failure Study Group.
N Engl J Med. 1997; (12): 828-34
Atrial natriuretic peptide, a hormone synthesized by the cardiac atria, increases the glomerular filtration rate by dilating afferent arterioles while constricting efferent arterioles. It has been shown to improve glomerular filtration, urinary output, and renal histopathology in laboratory animals with acute renal dysfunction. Anaritide is a 25-amino-acid synthetic form of atrial natriuretic peptide.
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