Mark L. Gonzalgo, M.D., Ph.D.
Publication Details
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Significance of preoperative PSA velocity in men with low serum PSA and normal DRE.
World J Urol. 2011; (1): 11-4
A PSA velocity (PSAV)>0.35 ng/ml/year approximately 10-15 years prior to diagnosis is associated with a greater risk of lethal prostate cancer. Some have recommended that a PSAV>0.35 ng/ml/year should prompt a prostate biopsy in men with a low serum PSA (<4 ng/ml) and benign DRE. However, less is known about the utility of this PSAV cutpoint for the prediction of treatment outcomes among men undergoing radical prostatectomy (RP).
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