Glenn M. Chertow
Publication Details
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Effluent volume in continuous renal replacement therapy overestimates the delivered dose of dialysis.
Clin J Am Soc Nephrol. 2011; (3): 467-75
Studies examining dose of continuous renal replacement therapy (CRRT) and outcomes have yielded conflicting results. Most studies considered the prescribed dose as the effluent rate represented by ml/kg per hour and reported this volume as a surrogate of solute removal. Because filter fouling can reduce the efficacy of solute clearance, the actual delivered dose may be substantially lower than the observed effluent rate.
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