James D. Brooks
Publication Details
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Identification of candidate prostate cancer genes through comparative expression-profiling of seminal vesicle.
Prostate. 2008; (11): 1248-56
Prostate cancer is the most frequently diagnosed cancer among men in the United States. In contrast, cancer of the seminal vesicle is exceedingly rare, despite that the prostate and seminal vesicle share similar histology, secretory function, androgen dependency, blood supply, and (in part) embryonic origin. We hypothesized that gene-expression differences between prostate and seminal vesicle might inform mechanisms underlying the higher incidence of prostate cancer.
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