Uri Ladabaum
Publication Details
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Citalopram provides little or no benefit in nondepressed patients with irritable bowel syndrome.
Clin Gastroenterol Hepatol. 2010; (1): 42-48.e1
Data on the benefit of selective serotonin reuptake inhibitors (SSRIs) in irritable bowel syndrome (IBS) are conflicting. The longitudinal relationship between clinical symptoms and sensitivity to barostat-mediated rectal distension in IBS remains unclear. We assessed the benefit of citalopram and explored the relationships between symptoms, quality of life (QOL), and rectal sensitivity to barostat distension in non-depressed IBS patients.
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