Kiran Kaur Khush, MD

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Publication Details

  • Nesiritide acutely increases pulmonary and systemic levels of nitric oxide in patients with pulmonary hypertension.

    Khush KK, De Marco T, Vakharia KT, Harmon C, Fineman JR, Chatterjee K, Michaels AD. J Card Fail. 2006; 12 (7): 507-13

    Pulmonary hypertension (PH) is characterized by decreased pulmonary vascular expression of nitric oxide (NOx), a vasodilator that increases levels of smooth muscle cyclic guanosine monophosphate (cGMP). This study investigated mechanisms by which the vasodilator B-type natriuretic peptide (BNP) affects the systemic and pulmonary vasculature in PH patients.

    PubMedID: 16952783

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