Lawrence Steinman
Publication Details
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Oligonucleotide dot-blot analysis of HLA-DQ beta alleles associated with multiple sclerosis.
J Neuroimmunol. 1991; (1): 61-5
Oligonucleotide probes were used to investigate the role of DQ beta molecules in susceptibility to multiple sclerosis. Although shared amino acid and nucleotide sequences in DQ beta 1 have been suggested to be critical in disease development, we find that the distribution of sequences corresponding to residues 71-77 is not greater in patients versus controls.
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