James D. Brooks

Publication Details

  • Silencing of pi-class glutathione S-transferase in MDA PCa 2a and MDA PCa 2b cells.

    Vidanes GM, Paton V, Wallen E, Peehl DM, Navone N, Brooks JD. Prostate. 2002; 51 (4): 225-30

    Loss of expression of the glutathione S-transferase-pi (GSTP1) is the most common genetic alteration described in human prostate cancer, occurring in virtually all tumors regardless of grade or stage. Of the available human prostate cancer cell lines, only LNCaP mirrors this phenotype. We investigated whether the prostate cancer cell lines MDA PCa 2a and MDA PCa 2b share this phenotype.

    PubMedID: 11987150

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