D. Craig Miller, M.D.
Publication Details
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Alterations in transmural strains adjacent to ischemic myocardium during acute midcircumflex occlusion.
J Thorac Cardiovasc Surg. 2005; (4): 791-803
Helically oriented left ventricular fibers assemble into transmural sheets, which are important for wall-thickening mechanics: 15% fiber shortening results in 40% cross-fiber left ventricular wall thickening and a 60% ejection fraction through sheet extension, thickening, and shear. Normal cardiac microstructure and strains are optimized; deviations could result in apoptosis and deleterious matrix remodeling, which degenerates into global cardiomyopathy. We studied alterations in transmural strains adjacent to ischemic myocardium during acute midcircumflex occlusion.
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