Lawrence "Rusty" Hofmann, MD

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Publication Details

  • Endovascular model of rabbit hindlimb ischemia: a platform to evaluate therapeutic angiogenesis.

    Liddell RP, Patel TH, Weiss CR, Lee DS, Matsuhashi T, Brown PR, Gabrielson KL, Rodriguez ER, Eng J, Kimura H, Hofmann LV. J Vasc Interv Radiol. 2005; 16 (7): 991-8

    Current animal hindlimb ischemia models involve surgical ligation of the femoral artery and delivery of therapeutic angiogenic agents into the adductor compartment. The authors hypothesize that an endovascular model of hindlimb ischemia would be a more appropriate platform, closely resembling atherosclerosis by occluding the vessel from within, causing less inflammation, wound healing and subsequent collateralization.

    PubMedID: 16002507

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