Geoffrey Gurtner
Publication Details
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Biologic brachytherapy: ex vivo transduction of microvascular beds for efficient, targeted gene therapy.
Plast Reconstr Surg. 2006; (1): 54-65; discussion 66-8
Gene therapy for cancer holds enormous therapeutic promise, but its clinical application has been limited by the inability to achieve targeted, high-level transgene expression with limited systemic toxicity. The authors have developed a novel method for delivering genes to microvascular free flaps (commonly used during reconstructive surgery) to avoid these problems.
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