Ronald L. Dalman MD, the Walter C. and Elsa R. Chidester Professor of Surgery
Publication Details
-
Efficacy and mechanism of angiotensin II receptor blocker treatment in experimental abdominal aortic aneurysms.
PLoS One. 2012; (12): e49642
Despite the importance of the renin-angiotensin (Ang) system in abdominal aortic aneurysm (AAA) pathogenesis, strategies targeting this system to prevent clinical aneurysm progression remain controversial and unproven. We compared the relative efficacy of two Ang II type 1 receptor blockers, telmisartan and irbesartan, in limiting experimental AAAs in distinct mouse models of aneurysm disease.
Help