Michael D. Dake
Publication Details
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Directed migration of smooth muscle cells to engineer plaque-resistant vein grafts.
J Endovasc Ther. 2005; (6): 667-75
To test the hypothesis that controlled perivascular release of tissue plasminogen activator (tPA) can generate cleaved extracellular matrix (ECM) chemotactic gradients to guide the migration of vascular smooth muscle cells (SMCs) away from the lumen, thereby limiting neointima formation.
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