D. Craig Miller, M.D.
Publication Details
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Presystolic mitral annular septal-lateral shortening is independent from left atrial and left ventricular contraction during acute volume depletion.
Eur J Cardiothorac Surg. 2009; (2): 236-42; discussion 242-3
The mitral annulus (MA) is a dynamic structure that joins the left atrium (LA) and left ventricle (LV), but it is unknown whether MA motion is coupled to the LA or the LV or neither of the two. Since a well orchestrated coordination of LA, MA and LV septal-lateral (S-L) dynamics is essential for efficient valve closure, we assessed their functional coupling in an experimental ovine model. To assess the coupling under a wide range of physiological conditions, data were acquired in normal and acutely volume depleted hearts.
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