Geoffrey Gurtner
Publication Details
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Treating chronic wound infections with genetically modified free flaps.
Plast Reconstr Surg. 2009; (4): 1157-68
The success of antimicrobial therapy has been impaired by the emergence of resistant bacterial strains. Antimicrobial peptides are ubiquitous proteins that are part of the innate immune system and are successful against such antibiotic-resistant microorganisms. The authors have previously demonstrated the feasibility of protein delivery via microvascular free flap gene therapy and here they examine this approach for recalcitrant infections.
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