Clinical Focus

• Cancer> Urologic Oncology
• Urology, Pediatric
• Pediatric Urology

Administrative Appointments

• Pediatric Urology Program Director, Stanford University Medical Center (2005 - 2009)
• Chair, Stanford University School of Medicine Department of Urology (1996 - present)
• Past Chair, American Academy Pediatrics Urology Section (2007 - 2008)
• Past Member, Residency Review Committee (2003 - 2009)
• Past President, American Board of Urology (2006 - 2007)

Honors and Awards

• • William and Flora Hewlett Foundation Fellow, Radcliffe Institute Center for Advanced Study at Harvard University (2008-2009)
• Featured Physician http://www.nlm.nih.gov/changingthefaceofmedicine/physicians/biography_293.html, National Library of Medicine (2003-2005)
• Asian American Faculty Award, Stanford University Asian American Association (2008)
• America's Top Doctors, Castle Connolly (2001- 2010)
• Best Doctors in America--Pediatric Urology, Naifeh & Smith; Woodward and White (1991-2, 1994-5, 1996-7)

Professional Education

Postdoctoral Advisee

Jens-Peter Volkmer

Graduate & Fellowship Program Affiliations

• Urology
• Pediatric Urology

Community & International Work

• First International WHO Consultation on Health Care Associated Infections in Urology (HCAIU) 
• Urologic Diseases in America 

Internet Links

• National Library of Medicine web link

Industry Relationships

Stanford is committed to ethical and transparent interactions with our industry partners. It is our policy to disclose payments of $5,000 or more, equity valued at $5,000 or more in a publicly traded company, or any equity in a privately held company, to physicians and scientists employed by Stanford University from companies or other commercial entities with which they interact as part of their professional activities. View Full Information

Current Research Interests

The timing for intervention in hydronephrosis in the infant and child is poorly understood. The interaction between urinary tract pressures and renal tubular and glomerular changes have not been well outlined. Our group has been interested in trying to define the parameters that may be involved in obstructive and infectious uropathies. We are also examining the effect of hormones on the urinary tract. We are applying the results of these findings to identify factors that could be markers of renal dysfunction. We have also collaborated with faculty at the Lucas Magnetic Resonance Center to develop new techniques with which to identify obstructive hydronephrosis. We have examined:

1. The effect of urinary flow rates and bladder fullness on renal pelvic and bladder pressures.
2. The effect of urinary tract infection on bladder and renal pelvic pressures.
3. The effect of vesicoureteral reflux on renal pelvic pressures.
4. The effect of anticholinergic drugs on bladder and renal pelvic pressures.
5. The effect of partial obstruction on renal pelvic pressures.
6. Urinary antibodies and intestinal bladder augmentation.
7. Ultrafast magnetic resonance imaging in a hydronephrotic rat model
8. Pathologic effect of inflammation and pressure on the kidney

Publications

• Evaluation of asymptomatic, atraumatic hematuria in children and adults. Tu WH, Shortliffe LD. Nat Rev Urol. 2010; 7 (4): 189-94
• Evaluation of dynamic contrast-enhanced MRI in detecting renal scarring in a rat injury model. Wang B, Sommer G, Spielman D, Shortliffe LM. J Magn Reson Imaging. 2010; 31 (5): 1132-6
• Top-down approach for evaluation of urinary tract infection. Wu HY, Shortliffe LD. Urology. 2010; 75 (3): 514-5
• Urinary tract infection in children: when to worry. Clark CJ, Kennedy WA, Shortliffe LD. Urol Clin North Am. 2010; 37 (2): 229-41
• Identification, molecular characterization, clinical prognosis, and therapeutic targeting of human bladder tumor-initiating cells. Chan KS, Espinosa I, Chao M, Wong D, Ailles L, Diehn M, Gill H, Presti J, Chang HY, van de Rijn M, Shortliffe L, Weissman IL. Proc Natl Acad Sci U S A. 2009; 106 (33): 14016-21