Matt van de Rijn
Academic Appointments
Key Documents
Contact Information
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Clinical Offices
Department of Pathology 300 Pasteur Dr L235 MC 5324 Stanford, CA 94305 Tel Work (650) 723-5252 Fax (650) 725-6902Practices at Stanford Hospital and Clinics and Lucile Packard Children's Hospital
- Academic Offices
Personal Information Email Tel (650) 498-7154Not for medical emergencies or patient use
Professional Overview
Clinical Focus
- Anatomic Pathology
- Sarcoma
Professional Education
| Residency: | Stanford University School of Medicine CA (1994) |
| Fellowship: | Stanford Hospital & Clinics CA (1994) |
| Board Certification: | Anatomic Pathology, American Board of Pathology (1993) |
| Medical Education: | Universiteit Van Amsterdam, Netherlands (1986) |
Internet Links
Scientific Focus
Current Research Interests
Our research focuses on gene microarray analysis of human soft tissue tumors (sarcomas). In addition we work with tissue microarrays to characterize large numbers of novel antisera raised against peptides derived from genes found to be of interest during gene array analysis. These genes are not only identified in sarcomas but, through collaborations with other laboratories, also in a large number of other human neoplasms, including breast, kidney, prostate, lung, and liver tumors.
Publications
- Anti-KIT monoclonal antibody inhibits imatinib-resistant gastrointestinal stromal tumor growth. Proc Natl Acad Sci U S A. 2013; (9): 3501-6
- Breakpoint analysis of transcriptional and genomic profiles uncovers novel gene fusions spanning multiple human cancer types. PLoS Genet. 2013; (4): e1003464
- Desktop transcriptome sequencing from archival tissue to identify clinically relevant translocations. Am J Surg Pathol. 2013; (6): 796-803
- Engineered SIRPα Variants as Immunotherapeutic Adjuvants to Anticancer Antibodies. Science. 2013
- Antibody therapy targeting the CD47 protein is effective in a model of aggressive metastatic leiomyosarcoma. Proc Natl Acad Sci U S A. 2012; (17): 6656-61
- CDX2 is an amplified lineage-survival oncogene in colorectal cancer. Proc Natl Acad Sci U S A. 2012; (46): E3196-205
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