Marion S. Buckwalter
Academic Appointments
- Assistant Professor - Med Center Line, Neurology & Neurological Sciences
- Member, Neurology & Neurological Sciences
- Assistant Professor - Med Center Line, Neurosurgery
Key Documents
Contact Information
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Clinical Offices
Neurology & Neurological Sciences 300 Pasteur Dr A343 MC 5235 Stanford, CA 94305 Tel Work (650) 723-4448 Fax (650) 723-4451
- Academic Offices
Personal Information Email Tel (650) 724-9098Not for medical emergencies or patient use
Professional Overview
Clinical Focus
- Neurology
- Neurologic Critical Care
Professional Education
| Fellowship: | UCSF Medical Center CA (2002) |
| Residency: | UCSF Medical Center CA (2000) |
| Board Certification: | United Council for Neurologic Subspecialties, Neurocritical Care (2008) |
| Board Certification: | Neurology, American Board of Psychiatry and Neurology (2001) |
| Internship: | UCSF Medical Center CA (1997) |
| Medical Education: | University of Michigan School of Medicine MI (1996) |
Graduate & Fellowship Program Affiliations
Internet Links
Scientific Focus
Current Research Interests
The goal of the Buckwalter Lab is to improve how people recover after a stroke. We use basic research to understand the cells, proteins, and genes that lead to successful recovery of function, and also how complications develop that impact quality of life after stroke. Ongoing projects are focused on understanding how inflammatory responses are regulated after a stroke and how to make recovery faster and better after stroke. With our collaborator Dr. Longo we have discovered a new drug that improves the speed and degree of recovery when mice are given the drug beginning three days after stroke. Developing it in animals to a point where it can be tried in people is a top priority. In terms of inflammation, we study how cells in the brain called astrocytes influence swelling and tissue cleanup after a stroke, and how similar cells in the lung influence stroke-induced immune insufficiency, which is a primary cause of pneumonias in stroke patients.
Clinical Trials
- Recruiting Diagnostic Utility of MRI in Intracerebral Hemorrhage
- Recruiting Computed Tomography Perfusion (CTP) to Predict Response to Recanalization in Ischemic Stroke Project (CRISP)
- Recruiting Efficacy and Safety Trial of Transcranial Laser Therapy Within 24 Hours From Stroke Onset (NEST-3)
- Recruiting Efficacy and Safety Study of Desmoteplase to Treat Acute Ischemic Stroke (DIAS-4)
- Recruiting Clot Lysis: Evaluating Accelerated Resolution of Intraventricular Hemorrhage Phase III
Publications
- A small molecule p75(NTR) ligand prevents cognitive deficits and neurite degeneration in an Alzheimer's mouse model. Neurobiol Aging. 2013; (8): 2052-63
- Delayed administration of a small molecule tropomyosin-related kinase B ligand promotes recovery after hypoxic-ischemic stroke. Stroke. 2012; (7): 1918-24
- Distal hypoxic stroke: a new mouse model of stroke with high throughput, low variability and a quantifiable functional deficit. J Neurosci Methods. 2012; (1): 31-40
- Stratification substantially reduces behavioral variability in the hypoxic-ischemic stroke model. Brain Behav. 2012; (5): 698-706
- The double-edged sword of inflammation after stroke: what sharpens each edge? Ann Neurol. 2012; (6): 729-31
- A comparison of cooling techniques to treat cardiac arrest patients with hypothermia. Stroke Res Treat. 2011: 690506
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