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Joshua M. Spin

Academic Appointments

Contact Information

  • Clinical Offices
    Cardiovascular Medicine 300 Pasteur Dr H2157 MC 5233 Stanford, CA 94305
    Tel Work (650) 725-8246 Fax (650) 724-4034
  • Academic Offices
    Personal Information
    Email Tel (650) 725-8246
    Not for medical emergencies or patient use

Professional Overview

Clinical Focus

  • Aortic Disease
  • Marfan Syndrome and Aortic Disorders
  • Cardiovascular Disease

Academic Appointments

Professional Education

Fellowship: Stanford University School of Medicine CA (2003)
Internship: Stanford University School of Medicine CA (1998)
Residency: Stanford University School of Medicine CA (2000)
Board Certification: Cardiovascular Disease, American Board of Internal Medicine (2003)
Medical Education: Boston University School of Medicine MA (1997)
BA: Cornell University, Biophysics (1989)
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Scientific Focus

Current Research and Scholarly Interests

Dr. Spin is pursuing fundamental issues relating to smooth muscle cell (SMC) biology. SMCs play crucial roles in vascular development, homeostasis, and disease. He has examined gene expression within the vascular wall, identifying patterns and pathways that characterized atherogenesis. He has also studied the biology of differentiation and phenotypic switching in vascular SMCs, first identifying differentially regulated genes associated with SMC lineage determination, and then focusing on the epigenetic regulation of SMC differentiation state. Most recently he has examined the role of microRNAs in the regulation of SMC phenotype, and studied the biology of aortic aneurysm development in mouse models.


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Publication Topics

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