{"result":[{"lastName":"Oderup","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Pathology"}],"primaryAppointment":"Postdoctoral Research fellow, Pathology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=9334&type=small&showNoImage","displayName":"Cecilia Oderup","firstName":"Cecilia","href":"http://med.stanford.edu/profiles/postdocs/researcher/Cecilia_Oderup","researchInterest":""},{"lastName":"Michie","clinicalFocus":[{"focus":"Anatomic Pathology"},{"focus":"Pathology and Laboratory Medicine"}],"appointments":[{"appointment":"Professor,Pathology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Pathology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=4707&type=small&showNoImage","displayName":"Sara Michie","firstName":"Sara","href":"http://stanfordhospital.org/profiles/Sara_Michie","researchInterest":"Lymphocyte/endothelial cell adhesion mechanisms involved in lymphocyte migration to sites of inflammation; regulation of expression of endothelial cell adhesion molecules."},{"lastName":"Strober","clinicalFocus":[{"focus":"Immunology and Rheumatology"},{"focus":"Rheumatology"}],"appointments":[{"appointment":"Professor,Medicine - Immunology & Rheumatology"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Professor,Medicine - Immunology & Rheumatology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=4152&type=small&showNoImage","displayName":"Samuel Strober","firstName":"Samuel","href":"http://stanfordhospital.org/profiles/Samuel_Strober","researchInterest":"Mechanisms of immune tolerance; regulatory processes in autoimmunity and transplantation and extrathymic T cell maturation."},{"lastName":"Lau","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Surgery"}],"primaryAppointment":"Postdoctoral Research fellow, Surgery","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=30657&type=small&showNoImage","displayName":"Audrey Lau","firstName":"Audrey","href":"http://med.stanford.edu/profiles/postdocs/researcher/Audrey_Lau","researchInterest":""},{"lastName":"Peltz","clinicalFocus":[],"appointments":[{"appointment":"Professor,Anesthesia"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Anesthesia","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=8527&type=small&showNoImage","displayName":"Gary Peltz","firstName":"Gary","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Gary_Peltz","researchInterest":"The laboratory develops and uses state of the art genomic methods to identify genetic factors affecting disease susceptibility, and to translate these findings into new treatments. We have developed a more efficient method for performing mouse genetic analysis, which has been used to analyze the genetic basis for 16 different biomedical traits. We are developing novel methods, and have developed a novel experimental platform that replaces mouse liver with functioning human liver tissue."},{"lastName":"Nguyen","clinicalFocus":[],"appointments":[{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Member,Stanford Cancer Institute","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=6893&type=small&showNoImage","displayName":"Vu Nguyen","firstName":"Vu","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Vu_Nguyen","researchInterest":""},{"lastName":"Negrin","clinicalFocus":[{"focus":"Blood and Marrow Transplantation"},{"focus":"Hematology"}],"appointments":[{"appointment":"Professor,Medicine - Blood & Marrow Transplantation"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Professor,Medicine - Blood & Marrow Transplantation","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=4138&type=small&showNoImage","displayName":"Robert Negrin","firstName":"Robert","href":"http://stanfordhospital.org/profiles/Robert_Negrin","researchInterest":"Our labaratory focuses on the study of immune recognition by T and NK cells with special emphasis on graft vs host disease and graft vs tumor reactions. We utilize both murine and human systems in an effort to enhance graft vs tumor reactions while controlling graft vs host disease. We have developed bioluminescence models in collaboration with the Contag laboratory to study the trafficking of immune effector cells with a special emphasis on NK, T and regulatory T cells."},{"lastName":"Bonham","clinicalFocus":[{"focus":"General Surgery"},{"focus":"Liver Transplantation"},{"focus":"Live-donor Liver Transplantation"},{"focus":"Pediatric Transplantation"},{"focus":"Intestinal Transplantation"},{"focus":"Kidney and Pancreas Transplantation"},{"focus":"Portal Hypertension"},{"focus":"Hepatobiliary Surgery"},{"focus":"Cancer of Biliary Tract"},{"focus":"Cancer, Liver"}],"appointments":[{"appointment":"Associate Professor - Med Center Line,Surgery - Multi-Organ Transplantation"},{"appointment":"Member,Child Health Research Institute"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Associate Professor - Med Center Line,Surgery - Multi-Organ Transplantation","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=3884&type=small&showNoImage","displayName":"Clark Bonham","firstName":"Clark","href":"http://stanfordhospital.org/profiles/Clark_Bonham","researchInterest":"Tolerance induction in liver transplantation.\r\nHepatocyte transplantation."},{"lastName":"Chien","clinicalFocus":[],"appointments":[{"appointment":"Professor,Microbiology & Immunology"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Professor,Microbiology & Immunology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=4121&type=small&showNoImage","displayName":"Yueh-hsiu Chien","firstName":"Yueh-Hsiu","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Yueh-Hsiu_Chien","researchInterest":"Contribution of T cells to immunocompetence and autoimmunity; how the immune system clears infection, avoids autoimmunity and how infection impacts on the development of immune responses."},{"lastName":"Fathman","clinicalFocus":[{"focus":"Immunology"},{"focus":"Immunology and Rheumatology"}],"appointments":[{"appointment":"Professor,Medicine - Immunology & Rheumatology"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Professor,Medicine - Immunology & Rheumatology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=4479&type=small&showNoImage","displayName":"C. Garrison Fathman","firstName":"C","href":"http://stanfordhospital.org/profiles/C_Fathman","researchInterest":"My lab of molecular and cellular immunology is interested in research in the general field of T cell activation and autoimmunity.   We use lentiviral mediated transduction of murine dendritic cells with immunoregulatory proteins for site specific and targeted immunotherapy. We have identified and characterized a gene (GRAIL) that seems to control T cell anergy.    We have recently characterized a gene (Deaf1) that seems to play a major role in peripheral tolerance in T1D."},{"lastName":"Huang","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Microbiology & Immunology"}],"primaryAppointment":"Postdoctoral Research fellow, Microbiology & Immunology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=13753&type=small&showNoImage","displayName":"Jun Huang","firstName":"Jun","href":"http://med.stanford.edu/profiles/postdocs/researcher/Jun_Huang","researchInterest":""},{"lastName":"Ewald","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Microbiology & Immunology"}],"primaryAppointment":"Postdoctoral Research fellow, Microbiology & Immunology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=19005&type=small&showNoImage","displayName":"Sarah Ewald","firstName":"Sarah","href":"http://med.stanford.edu/profiles/postdocs/researcher/Sarah_Ewald","researchInterest":""},{"lastName":"Parnes","clinicalFocus":[],"appointments":[{"appointment":"Emeritus Faculty, Acad Council,Medicine - Immunology & Rheumatology"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Emeritus Faculty, Acad Council,Medicine - Immunology & Rheumatology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=4487&type=small&showNoImage","displayName":"Jane Parnes","firstName":"Jane","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Jane_Parnes","researchInterest":"The lab is studying the mechanisms controlling B cell responsiveness and the balance between tolerance and autoimmunity.  B cells deficient in CD72 are hyperresponsive to stimulation through the B cell receptor.  We are examining the alterations in B cell signaling in these B cells and the mechanisms by which CD72 deficiency partially abrogates anergic tolerance.  We hope to learn how deficiency in CD72 leads to spontaneous autoimmunity and increased susceptibility to induced autoimmune disease."},{"lastName":"Maecker","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor (Research),Microbiology & Immunology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Associate Professor (Research),Microbiology & Immunology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=25058&type=small&showNoImage","displayName":"Holden Maecker","firstName":"Holden","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Holden_Maecker","researchInterest":"I'm interested in immune monitoring of T cell responses to chronic pathogens such as CMV, and the correlation of T cell response signatures with disease protection."},{"lastName":"Rouse","clinicalFocus":[],"appointments":[{"appointment":"Professor - Med Center Line,Pathology"}],"primaryAppointment":"Professor - Med Center Line,Pathology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=4491&type=small&showNoImage","displayName":"Robert V Rouse","firstName":"Robert","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Robert_Rouse","researchInterest":"My recent research efforts are currently focused in the field of applications of immunohistology to the diagnosis of human neoplasms. This work is predominantly aimed at characterizing markers for the identification of non-lymphoid neoplasms and at establishing criteria for their evaluation in diagnostic situations."},{"lastName":"Utz","clinicalFocus":[{"focus":"Immunology and Rheumatology"},{"focus":"Rheumatology"}],"appointments":[{"appointment":"Professor,Medicine - Immunology & Rheumatology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Medicine - Immunology & Rheumatology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=4001&type=small&showNoImage","displayName":"Paul Utz","firstName":"Paul","href":"http://stanfordhospital.org/profiles/Paul_Utz","researchInterest":"The long-term research goal of Dr. Utz\u0092s laboratory is (1) to develop a better understanding of the pathogenic mechanisms underlying systemic lupus erythematosus (SLE) and other autoimmune diseases by exploring signaling pathways that are activated during apoptosis; and (2) to better understand the complicated process of programmed cell death."},{"lastName":"Cole","clinicalFocus":[],"appointments":[{"appointment":"MD Student, School of Medicine"}],"primaryAppointment":"MD Student, School of Medicine","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=23753&type=small&showNoImage","displayName":"Tyler Cole","firstName":"Tyler","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Tyler_Cole","researchInterest":""},{"lastName":"Monack","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Microbiology & Immunology"},{"appointment":"Member,Child Health Research Institute"}],"primaryAppointment":"Associate Professor,Microbiology & Immunology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=8324&type=small&showNoImage","displayName":"Denise M. Monack","firstName":"Denise","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Denise_Monack","researchInterest":"The primary focus of my research is to understand the genetic and molecular mechanisms of intracellular bacterial pathogenesis.  We use two model systems, Salmonella typhimurium and Francisella tularensis, to study the complex host-pathogen interactions.  Ultimately we would like to understand how Salmonella persists within certain hosts for years in the face of a robust immune response and how F. tularensis, a stealth invader, can cause a rapid, lethal infection."},{"lastName":"Goronzy","clinicalFocus":[{"focus":"Vasculitis"},{"focus":"Rheumatoid Arthritis"},{"focus":"Immunology"}],"appointments":[{"appointment":"Professor,Medicine - Immunology & Rheumatology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Medicine - Immunology & Rheumatology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=15394&type=small&showNoImage","displayName":"Jorg Goronzy","firstName":"Jorg","href":"http://stanfordhospital.org/profiles/Jorg_Goronzy","researchInterest":""},{"lastName":"Bollyky","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Medicine - Infectious Diseases"},{"appointment":"Member,Child Health Research Institute"}],"primaryAppointment":"Assistant Professor,Medicine - Infectious Diseases","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=35956&type=small&showNoImage","displayName":"Paul Bollyky","firstName":"Paul","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Paul_Bollyky","researchInterest":"Our research is focused on the role of extracellular matrix (ECM) in inflammation and infection.    In particular, we study how the ECM in injured and healing tissues provides contextual cues that drive the behavior of regulatory T-cells and other leukocytes. Our goals are 1. to understand how the matrix contributes both to normal wound healing and to immune dysregulation, such as that seen in asthma and autoimmunity, and 2. to devise novel strategies and tools to promote immune tolerance."}]}