{"result":[{"lastName":"Sarin","clinicalFocus":[{"focus":"Dermatology"},{"focus":"Precision Dermatology"},{"focus":"Skin Cancers"},{"focus":"Adverse Drug Reactions"}],"appointments":[{"appointment":"Clinical Assistant Professor,Dermatology"}],"primaryAppointment":"Clinical Assistant Professor,Dermatology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=33859&type=small&showNoImage","displayName":"Kavita Sarin","firstName":"Kavita","href":"http://stanfordhospital.org/profiles/Kavita_Sarin","researchInterest":""},{"lastName":"Artandi","clinicalFocus":[{"focus":"Medical Oncology"}],"appointments":[{"appointment":"Professor,Medicine - Hematology"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Member,Bio-X"},{"appointment":"Professor,Biochemistry"}],"primaryAppointment":"Professor,Medicine - Hematology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=3848&type=small&showNoImage","displayName":"Steven Artandi","firstName":"Steven","href":"http://stanfordhospital.org/profiles/Steven_Artandi","researchInterest":"Telomeres are nucleoprotein complexes that protect chromosome ends and shorten with cell division and aging. We are interested in how telomere shortening influences cancer, stem cell function and genomic stability. Telomerase is a reverse transcriptase that synthesizes telomere repeats and is expressed in stem cells and in cancer. We have found that telomerase also regulates stem cells and we are pursuing the function of telomerase through diverse genetic and biochemical approaches."},{"lastName":"Huang","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Microbiology & Immunology"}],"primaryAppointment":"Postdoctoral Research fellow, Microbiology & Immunology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=23069&type=small&showNoImage","displayName":"Shenglin Huang","firstName":"Shenglin","href":"http://med.stanford.edu/profiles/postdocs/researcher/Shenglin_Huang","researchInterest":""},{"lastName":"Reijo Pera","clinicalFocus":[],"appointments":[{"appointment":"Professor,Obstetrics & Gynecology - Obstetrics & Gynecology - Institutes"},{"appointment":"Member,Child Health Research Institute"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Professor,Obstetrics & Gynecology - Obstetrics & Gynecology - Institutes","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=8036&type=small&showNoImage","displayName":"Renee A. Reijo Pera, Ph.D.","firstName":"Renee","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Renee_Reijo Pera","researchInterest":"The Reijo Pera Laboratory is focused on pluripotent stem cells and regenerative medicine with an emphasis on understanding key cell fate decisions in early human development. In particular, we examine early events such as the generation of pluripotent stem cells, somatic and germ cell lineages and pathologies that arise in development."},{"lastName":"Sebastiano","clinicalFocus":[],"appointments":[{"appointment":"Instructor,Obstetrics & Gynecology - Obstetrics & Gynecology - Institutes"}],"primaryAppointment":"Instructor,Obstetrics & Gynecology - Obstetrics & Gynecology - Institutes","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=12351&type=small&showNoImage","displayName":"Vittorio Sebastiano","firstName":"Vittorio","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Vittorio_Sebastiano","researchInterest":""},{"lastName":"Xie","clinicalFocus":[],"appointments":[{"appointment":"Ph.D., Biochemistry"}],"primaryAppointment":"Ph.D., Biochemistry","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=19942&type=small&showNoImage","displayName":"Kathleen Xie","firstName":"Kathleen","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Kathleen_Xie","researchInterest":""},{"lastName":"Wernig","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Pathology - Stem Cell Institute"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Child Health Research Institute"}],"primaryAppointment":"Assistant Professor,Pathology - Stem Cell Institute","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=10445&type=small&showNoImage","displayName":"Marius Wernig","firstName":"Marius","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Marius_Wernig","researchInterest":"Epigenetic Reprogramming, Direct conversion of fibroblasts into neurons, Pluripotent Stem Cells, Neural Differentiation: implications in development and regenerative medicine"},{"lastName":"Leung","clinicalFocus":[{"focus":"Dermatology"}],"appointments":[{"appointment":"Instructor,Dermatology"}],"primaryAppointment":"Instructor,Dermatology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=23406&type=small&showNoImage","displayName":"Thomas Leung","firstName":"Thomas","href":"http://stanfordhospital.org/profiles/Thomas_Leung","researchInterest":""},{"lastName":"Russell","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Medical fellow, Medicine"}],"primaryAppointment":"Postdoctoral Medical fellow, Medicine","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=23331&type=small&showNoImage","displayName":"Jeffrey Russell","firstName":"Jeffrey","href":"http://med.stanford.edu/profiles/postdocs/researcher/Jeffrey_Russell","researchInterest":""},{"lastName":"So","clinicalFocus":[{"focus":"Liver Cancer"},{"focus":"Liver Cancer - Surgery"},{"focus":"Gastrointestinal Cancers - Surgical Oncology"},{"focus":"General Surgery"}],"appointments":[{"appointment":"Professor - Med Center Line,Surgery - General Surgery"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Professor - Med Center Line,Surgery - General Surgery","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=4206&type=small&showNoImage","displayName":"Samuel So","firstName":"Samuel","href":"http://stanfordhospital.org/profiles/Samuel_So","researchInterest":"Through a 3 pronged comprehensive program: translational and clinical research, early detection and treatment, and promoting education, awareness and immunization, we are working towards the development of new strategies that will lead to the elimination of hepatitis B worldwide and reduce the threat and incidence of liver cancer. Our current research efforts focus on evaluating potential new diagnostic and treatment markers and novel targeted therapy for primary liver cancer."},{"lastName":"Poultsides","clinicalFocus":[{"focus":"Liver Neoplasms"},{"focus":"Pancreas Neoplasms"},{"focus":"Gastric Neoplasms"},{"focus":"Bile Duct Neoplasms"},{"focus":"Gallbladder Neoplasms"},{"focus":"Sarcoma"},{"focus":"Adrenal Neoplasms"},{"focus":"General Surgery"}],"appointments":[{"appointment":"Assistant Professor - Med Center Line,Surgery - General Surgery"}],"primaryAppointment":"Assistant Professor - Med Center Line,Surgery - General Surgery","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=14355&type=small&showNoImage","displayName":"George A. Poultsides, MD","firstName":"George","href":"http://stanfordhospital.org/profiles/George_Poultsides","researchInterest":"Clinical trials of experimental therapeutics and outcomes analysis following combined modality treatment of hepatic, pancreatic, and gastrointestinal malignancies."},{"lastName":"Ronald","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Radiology"}],"primaryAppointment":"Postdoctoral Research fellow, Radiology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=13095&type=small&showNoImage","displayName":"John Ronald","firstName":"John","href":"http://med.stanford.edu/profiles/postdocs/researcher/John_Ronald","researchInterest":"Development of novel gene expression systems for potent, tumor-specific gene therapy of cancer, and to link therapeutic gene expression with imaging reporter gene expression in order to longitudinally track treatment efficacy in living subjects using bioluminescence imaging and positron emission tomography. Emphasis has also been on labeling therapeutic cells with imaging probes or reporter genes to track the fate of these cells in both small animal models and human subjects."},{"lastName":"Paulmurugan","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor (Research),Radiology - Diagnostic Radiology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Assistant Professor (Research),Radiology - Diagnostic Radiology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=14774&type=small&showNoImage","displayName":"Ramasamy Paulmurugan","firstName":"Ramasamy","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Ramasamy_Paulmurugan","researchInterest":""},{"lastName":"Wong","clinicalFocus":[],"appointments":[{"appointment":"MS, Dean's Office"},{"appointment":"Postdoctoral Medical fellow, Medicine"}],"primaryAppointment":"MS, Dean's Office","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=34361&type=small&showNoImage","displayName":"Robert Wong","firstName":"Robert","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Robert_Wong","researchInterest":""},{"lastName":"Fan Minogue","clinicalFocus":[],"appointments":[{"appointment":"MS, Dean's Office"}],"primaryAppointment":"MS, Dean's Office","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=9608&type=small&showNoImage","displayName":"Hua Fan Minogue","firstName":"Hua","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Hua_Fan Minogue","researchInterest":"Detecting protein-protein interactions during cell signaling using molecular imaging approaches, translating bench-side knowledges in cell biology and cancer biology into guidance for bedside therapy to benefit patient care and human health. \r\n Recently,utilizing bioinformatics tools to understand cell signaling network in cancer development. Data mining and modeling for extraction of hidden relationship in cancer network. Whole genome sequencing, GWAS and PGx for individualized cancer therapy"},{"lastName":"Chavez","clinicalFocus":[],"appointments":[{"appointment":"Basic Life Science Research Associate,Stem Cell - Stem Cell Biology and Regenerative Medicine Institute"}],"primaryAppointment":"Basic Life Science Research Associate,Stem Cell - Stem Cell Biology and Regenerative Medicine Institute","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=9821&type=small&showNoImage","displayName":"Shawn L. Chavez","firstName":"Shawn","href":"http://stanfordhospital.org/profiles/Shawn_Chavez","researchInterest":"My current work is focused on the role of DNA Methyltransferases (DNMTs) in human germ cell differentiation and imprinting. Previous studies in rodents suggest that DNA methylation may contribute to the regulation of germ cell differentiation. Therefore, we are evaluating the expression and function of DNMTs in hESC-derived germ cells throughout development and determining their importance for normal germ cell differentiation and imprinting."},{"lastName":"Lu","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Surgery"}],"primaryAppointment":"Postdoctoral Research fellow, Surgery","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=24347&type=small&showNoImage","displayName":"Wenjing Lu","firstName":"Wenjing","href":"http://med.stanford.edu/profiles/postdocs/researcher/Wenjing_Lu","researchInterest":""},{"lastName":"Ford","clinicalFocus":[{"focus":"Cancer Genetics"},{"focus":"Gastrointestinal Cancers - Genetics"},{"focus":"Gastrointestinal Cancers - Medical Oncology"},{"focus":"Breast Cancer - Genetics"},{"focus":"Ovarian Cancer - Genetics"},{"focus":"Medical Oncology"}],"appointments":[{"appointment":"Associate Professor,Medicine - Oncology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Associate Professor,Genetics"},{"appointment":"Associate Professor (By courtesy),Pediatrics"}],"primaryAppointment":"Associate Professor,Medicine - Oncology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=4066&type=small&showNoImage","displayName":"James Ford","firstName":"James","href":"http://stanfordhospital.org/profiles/James_Ford","researchInterest":"Mammalian DNA repair and DNA damage inducible responses; p53 tumor suppressor gene; transcription in nucleotide excision repair and mutagenesis; genetic determinants of cancer cell sensitivity to DNA\u000bdamage; genetics of inherited cancer susceptibility syndromes and human GI malignancies; clinical cancer genetics of BRCA1 and BRCA2 breast cancer and mismatch repair deficient colon cancer."},{"lastName":"Alli","clinicalFocus":[],"appointments":[{"appointment":"Instructor,Medicine - Oncology"}],"primaryAppointment":"Instructor,Medicine - Oncology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=9711&type=small&showNoImage","displayName":"Elizabeth Alli","firstName":"Elizabeth","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Elizabeth_Alli","researchInterest":"I am interested in identifying targeted therapies for triple-negative breast cancers and developing a novel strategy of biomarker-based chemoprevention for hereditary cancers that arise due to mutations in the Breast Cancer Susceptibility Gene 1 (BRCA1)."},{"lastName":"Gambhir","clinicalFocus":[{"focus":"Nuclear Medicine"},{"focus":"Radiology"},{"focus":"PET Scan"}],"appointments":[{"appointment":"Professor,Radiology - Diagnostic Radiology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Professor (By courtesy),Bioengineering"},{"appointment":"Professor (By courtesy),Materials Science and Engineering - Engineering Materials Science"}],"primaryAppointment":"Professor,Radiology - Diagnostic Radiology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=3971&type=small&showNoImage","displayName":"Sanjiv Sam Gambhir, MD, PhD","firstName":"Sanjiv","href":"http://stanfordhospital.org/profiles/Sanjiv_Gambhir","researchInterest":"My laboratory focuses on merging advances in molecular biology with those in biomedical imaging to advance the new field of molecular imaging. Methods to image gene expression in living subjects have been developed. Newer approaches to image fundamental cellular events with optical and radiolabeled probes are under active investigation. These imaging approaches are expected to have a fundamental impact in the study of cancer biology, as well as in molecular therapeutics including gene therapy"},{"lastName":"Calos","clinicalFocus":[],"appointments":[{"appointment":"Professor,Genetics"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Genetics","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=4100&type=small&showNoImage","displayName":"Michele Calos","firstName":"Michele","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Michele_Calos","researchInterest":"My lab is developing innovative gene and cell therapies for genetic diseases, with a focus on stem cell therapies and regenerative medicine. \r\n\r\nWe have created novel methods for inserting therapeutic genes into the chromosomes at specific places by using homologous recombination and recombinase enzymes. \r\n\r\nWe are working on two forms of muscular dystrophy. \r\n\r\nWe created induced pluripotent stem cells from patient fibroblasts, added therapeutic genes, differentiated, and engrafted the cells."},{"lastName":"Felsher","clinicalFocus":[{"focus":"Hodgkin's Disease"},{"focus":"Hodgkin's Disease - Hematology"},{"focus":"Hodgkin's Disease - Medical Oncology"},{"focus":"Lymphoma "},{"focus":"Oncology (Cancer)"},{"focus":"Medical Oncology"}],"appointments":[{"appointment":"Professor,Medicine - Oncology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Professor,Pathology"}],"primaryAppointment":"Professor,Medicine - Oncology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=5931&type=small&showNoImage","displayName":"Dean W. Felsher","firstName":"Dean","href":"http://stanfordhospital.org/profiles/Dean_Felsher","researchInterest":"My laboratory investigates how oncogenes initiate and sustain tumorigenesis. I have developed model systems whereby I can conditionally activate oncogenes in normal human and mouse cells in tissue culture or in specific tissues of transgenic mice. In particular using the tetracycline regulatory system, I have generated a conditional model system for MYC-induced tumors. I have shown that cancers caused by the conditional over-expression of the MYC proto-oncogene regress with its inactivation."}]}