{"result":[{"lastName":"Tompkins","clinicalFocus":[{"focus":"Infectious Diseases"},{"focus":"Internal Medicine"},{"focus":"hospital epidemiology"}],"appointments":[{"appointment":"Professor,Medicine - Infectious Diseases"},{"appointment":"Professor,Microbiology & Immunology"}],"primaryAppointment":"Professor,Medicine - Infectious Diseases","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=4603&type=small&showNoImage","displayName":"Lucy Tompkins","firstName":"Lucy","href":"http://stanfordhospital.org/profiles/Lucy_Tompkins","researchInterest":"Molecular epidemiology, hospital epidemiology, quality improvement in healthcare associated infections."},{"lastName":"Theriot","clinicalFocus":[],"appointments":[{"appointment":"Professor,Biochemistry"},{"appointment":"Professor,Microbiology & Immunology"}],"primaryAppointment":"Professor,Biochemistry","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=4432&type=small&showNoImage","displayName":"Julie Theriot","firstName":"Julie","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Julie_Theriot","researchInterest":"We study the interactions between infectious bacteria and the human host cell actin cytoskeleton. Listeria monocytogenes and Shigella flexneri are unrelated food-borne bacterial pathogens that share a common mechanism of invasion and actin-dependent intercellular spread in epithelial cells. Our studies fall into three broad areas: the biochemical basis of actin-based motility by these bacteria, the biophysical mechanism of force generation, and the evolutionary origin of pathogenesis."},{"lastName":"Parsonnet","clinicalFocus":[{"focus":"Infectious Disease"},{"focus":"Tuberculosis"},{"focus":"Infectious Diarrheal Disease"},{"focus":"Helicobacter"},{"focus":"Parasitic Diseases"}],"appointments":[{"appointment":"Professor,Medicine - Infectious Diseases"},{"appointment":"Member,Child Health Research Institute"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Professor,Health Research & Policy"}],"primaryAppointment":"Professor,Medicine - Infectious Diseases","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=4495&type=small&showNoImage","displayName":"Julie Parsonnet","firstName":"Julie","href":"http://stanfordhospital.org/profiles/Julie_Parsonnet","researchInterest":"I am interested in the long-term consequences of chronic interactions between the human host and the microbial world.  Recently, we have focused most heavily on Helicobacter pylori, tuberculosis and helminth infections.  I also remain strongly interested in diarrheal diseases, particularly in the developing world, and in sanitation and hygiene."},{"lastName":"Falkow","clinicalFocus":[],"appointments":[{"appointment":"Professor Emeritus,Microbiology & Immunology"},{"appointment":"Emeritus Faculty, Acad Council,Microbiology & Immunology"}],"primaryAppointment":"Professor Emeritus,Microbiology & Immunology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=4488&type=small&showNoImage","displayName":"Stanley Falkow","firstName":"Stanley","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Stanley_Falkow","researchInterest":"Dr. Falkow is no longer taking students or postdoctoral fellows in his laboratory.  \r\n\r\nPlease contact either Denise Monack (dmonack@stanford.edu) or Manuel Amieva (amieva@stanford.edu)."},{"lastName":"Meyer","clinicalFocus":[],"appointments":[{"appointment":"Professor,Chemical and Systems Biology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Chemical and Systems Biology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=4007&type=small&showNoImage","displayName":"Tobias Meyer","firstName":"Tobias","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Tobias_Meyer","researchInterest":"CELLULAR INFORMATION PROCESSING  The main problem in signal transduction is to understand how different receptor-stimuli specifically control diverse cell functions. We are using automated microscopy, live-cell fluorescent biosensors and perturbations of predicted signaling proteins to systematically dissect signaling networks.  This allows us to identify signaling modules and to elucidate and ultimately model the flow of cellular information."},{"lastName":"Chang","clinicalFocus":[],"appointments":[{"appointment":"Instructor,Medicine - Infectious Diseases"}],"primaryAppointment":"Instructor,Medicine - Infectious Diseases","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=9020&type=small&showNoImage","displayName":"Alicia H. Chang","firstName":"Alicia","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Alicia_Chang","researchInterest":"I study infectious diseases in marginalized and vulnerable populations, with a specific focus on gastrointestinal infections and tuberculosis. My projects include assessing outcomes in patients, elucidating determinants of active tuberculosis, and studying the effects of chronic disease and co-infections and host immune response."},{"lastName":"Wong","clinicalFocus":[],"appointments":[{"appointment":"Professor,Neurosurgery"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Professor,Neurosurgery","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=7143&type=small&showNoImage","displayName":"Albert J. Wong, M.D.","firstName":"Albert","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Albert_Wong","researchInterest":"Our goal is to define targets for cancer therapeutics by identifying alterations in signal transduction proteins. We first identified a naturally occurring  mutant EGF receptor (EGFRvIII) and then delineated its unique signal transduction pathway. This work led to the identification of Gab1 followed by the discovery that JNK is constitutively active in tumors. We intiated using altered proteins as the target for vaccination, where an EGFRvIII based vaccine appears to be highly effective."},{"lastName":"Sarinay Cenik","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Developmental Biology"}],"primaryAppointment":"Postdoctoral Research fellow, Developmental Biology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=37141&type=small&showNoImage","displayName":"Elif Sarinay Cenik","firstName":"Elif","href":"http://med.stanford.edu/profiles/postdocs/researcher/Elif_Sarinay Cenik","researchInterest":""},{"lastName":"Monack","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Microbiology & Immunology"},{"appointment":"Member,Child Health Research Institute"}],"primaryAppointment":"Associate Professor,Microbiology & Immunology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=8324&type=small&showNoImage","displayName":"Denise M. Monack","firstName":"Denise","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Denise_Monack","researchInterest":"The primary focus of my research is to understand the genetic and molecular mechanisms of intracellular bacterial pathogenesis.  We use two model systems, Salmonella typhimurium and Francisella tularensis, to study the complex host-pathogen interactions.  Ultimately we would like to understand how Salmonella persists within certain hosts for years in the face of a robust immune response and how F. tularensis, a stealth invader, can cause a rapid, lethal infection."},{"lastName":"Giaccia","clinicalFocus":[],"appointments":[{"appointment":"Professor,Radiation Oncology - Radiation and Cancer Biology"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Professor (By courtesy),Obstetrics & Gynecology"},{"appointment":"Professor (By courtesy),Surgery"}],"primaryAppointment":"Professor,Radiation Oncology - Radiation and Cancer Biology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=4141&type=small&showNoImage","displayName":"Amato J. Giaccia","firstName":"Amato","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Amato_Giaccia","researchInterest":"During the last five years, we have identified several small molecules that kill VHL deficient renal cancer cells through a synthetic lethal screening approach. Another major interest of my laboratory is in identifying hypoxia-induced genes involved in invasion and metastases. We are also investigating how hypoxia regulates gene expression epigenetically."},{"lastName":"Sibley","clinicalFocus":[{"focus":"Anatomic Pathology"},{"focus":"Pathology"}],"appointments":[{"appointment":"Professor,Pathology"}],"primaryAppointment":"Professor,Pathology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=4113&type=small&showNoImage","displayName":"Richard Sibley","firstName":"Richard","href":"http://stanfordhospital.org/profiles/Richard_Sibley","researchInterest":"Immunologic mechanism of rejection in humans and animal, models of organ transplantation; histological definition of clinical pathology studies of various renal disorders."},{"lastName":"Hu","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Obstetrics & Gynecology"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Associate Professor,Obstetrics & Gynecology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=10405&type=small&showNoImage","displayName":"Mickey Hu","firstName":"Mickey","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Mickey_Hu","researchInterest":""},{"lastName":"Teruel","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Chemical and Systems Biology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Assistant Professor,Chemical and Systems Biology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=14171&type=small&showNoImage","displayName":"Mary Frances Nunez Teruel","firstName":"Mary","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Mary_Teruel","researchInterest":"The Teruel Lab uses a combination of engineering and biological approaches including high-throughput screening of RNAi and DNA construct libraries, targeted mass spectrometry, live-cell fluorescence microscopy, and bioinformatics to investigate the systems biology of cell differentiation and cell signaling with particular focus on uncovering the molecular mechanisms underlying insulin resistance, diabetes, and obesity."},{"lastName":"Cole","clinicalFocus":[],"appointments":[{"appointment":"MD Student, School of Medicine"}],"primaryAppointment":"MD Student, School of Medicine","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=23753&type=small&showNoImage","displayName":"Tyler Cole","firstName":"Tyler","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Tyler_Cole","researchInterest":""},{"lastName":"Cohen","clinicalFocus":[],"appointments":[{"appointment":"Professor,Genetics"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Professor,Medicine"}],"primaryAppointment":"Professor,Genetics","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=4481&type=small&showNoImage","displayName":"Stanley N. Cohen, MD","firstName":"Stanley","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Stanley_Cohen","researchInterest":"We study RNA decay and mechanisms that affect microbial antibiotic resistance, as well as the exploitation of host genes by pathogens. A small bioinformatics team within our lab has developed knowledge based systems to aid in investigations of gene expression on a genome-wide basis."},{"lastName":"Chien","clinicalFocus":[],"appointments":[{"appointment":"Professor,Microbiology & Immunology"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Professor,Microbiology & Immunology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=4121&type=small&showNoImage","displayName":"Yueh-hsiu Chien","firstName":"Yueh-Hsiu","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Yueh-Hsiu_Chien","researchInterest":"Contribution of T cells to immunocompetence and autoimmunity; how the immune system clears infection, avoids autoimmunity and how infection impacts on the development of immune responses."},{"lastName":"Yan","clinicalFocus":[],"appointments":[{"appointment":"Instructor,Medicine - Hematology"}],"primaryAppointment":"Instructor,Medicine - Hematology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=13412&type=small&showNoImage","displayName":"Kelley Yan","firstName":"Kelley","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Kelley_Yan","researchInterest":""},{"lastName":"Lowndes","clinicalFocus":[],"appointments":[{"appointment":"Ph.D., Dean's Office"}],"primaryAppointment":"Ph.D., Dean's Office","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=20027&type=small&showNoImage","displayName":"Molly Lowndes","firstName":"Molly","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Molly_Lowndes","researchInterest":""},{"lastName":"Marinkovich","clinicalFocus":[{"focus":"Dermatology"},{"focus":"Autoimmune Blistering Diseases"},{"focus":"Epidermolysis Bullosa"}],"appointments":[{"appointment":"Associate Professor,Dermatology"},{"appointment":"Member,Child Health Research Institute"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Associate Professor,Dermatology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=4217&type=small&showNoImage","displayName":"M. Peter Marinkovich","firstName":"Matt","href":"http://stanfordhospital.org/profiles/Matt_Marinkovich","researchInterest":"The Marinkovich lab studies the function of epithelial extracellular matrix molecules, including integrins, collagens and laminins in epithelial development and carcinoma progression.  We apply our discoveries in this area towards development of molecular therapies for carcinomas, hair disease and inherited epithelial adhesive disorders."},{"lastName":"Nelson","clinicalFocus":[],"appointments":[{"appointment":"Professor,Biology (School of Humanities and Sciences)"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Professor,Molecular & Cellular Physiology"}],"primaryAppointment":"Professor,Biology (School of Humanities and Sciences)","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=4323&type=small&showNoImage","displayName":"W James Nelson","firstName":"W James","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/W James_Nelson","researchInterest":"Our research objectives are to understand the cellular mechanisms involved in the development and maintenance of epithelial cell polarity. Polarized epithelial cells play fundamental roles in the ontogeny and function of a variety of tissues and organs."},{"lastName":"Levy","clinicalFocus":[],"appointments":[{"appointment":"Professor (Research),Medicine - Oncology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Professor (Research),Medicine - Oncology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=4307&type=small&showNoImage","displayName":"Shoshana Levy","firstName":"Shoshana","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Shoshana_Levy","researchInterest":"Our research focuses on the mechanism of action of tetraspanins, an evolutionary conserved, widely expressed multi-gene family. We study a prototype, CD81, a molecule implicated in the pathogenesis of two major human diseases: hepatitis C virus (HCV) and malaria."},{"lastName":"Kuo","clinicalFocus":[{"focus":"Medical Oncology"}],"appointments":[{"appointment":"Professor,Medicine - Hematology"},{"appointment":"Member,Child Health Research Institute"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Member,Bio-X"},{"appointment":"Professor (By courtesy),Chemical and Systems Biology"}],"primaryAppointment":"Professor,Medicine - Hematology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=5906&type=small&showNoImage","displayName":"Calvin Kuo","firstName":"Calvin","href":"http://stanfordhospital.org/profiles/Calvin_Kuo","researchInterest":"We explore angiogenesis, cancer genomics, intestinal stem cells, and hepatic glucose metabolism.  Angiogenesis projects include endothelial miRNA and GPCR ko mice, blood-brain barrier regulation, stroke therapeutics and anti-angiogenic cancer therapy.  Intestinal stem cell projects use primary intestinal culture and mouse genetics to study injury-inducible vs homeostatic stem cells.  We use primary organoid cultures of diverse tissues for oncogene functional screening and therapeutics discovery."}]}