{"result":[{"lastName":"Helms","clinicalFocus":[],"appointments":[{"appointment":"Professor,Surgery - Plastic & Reconstructive Surgery"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Surgery - Plastic & Reconstructive Surgery","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=6152&type=small&showNoImage","displayName":"Jill Helms","firstName":"Jill","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Jill_Helms","researchInterest":"Dr. Helms' research interests center around regenerative medicine and craniofacial development."},{"lastName":"Wysocka","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Chemical and Systems Biology"},{"appointment":"Associate Professor,Developmental Biology"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Associate Professor,Chemical and Systems Biology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=7764&type=small&showNoImage","displayName":"Joanna Wysocka","firstName":"Joanna","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Joanna_Wysocka","researchInterest":"Research in our lab focuses on mechanisms of epigenetic regulation in differentiation and development. In particular, we are studying the function of histone modifying enzymes in embryonic stem cell self-renewal and in early cell fate decisions. We are interested in the role of chromatin modifications in establishment and maintenance of gene expression patterns during normal and pathological development, and in nuclear reprogramming."},{"lastName":"Gupta","clinicalFocus":[{"focus":"Dermatology"},{"focus":"Psoriasis"},{"focus":"Atopic Dermatitis"},{"focus":"Scleroderma, Localized"},{"focus":"Lupus Erythematosus, Cutaneous"},{"focus":"Lupus Erythematosus, Discoid"},{"focus":"Dermatomyositis"}],"appointments":[{"appointment":"Clinical Assistant Professor,Dermatology"}],"primaryAppointment":"Clinical Assistant Professor,Dermatology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=8514&type=small&showNoImage","displayName":"Rajnish Gupta","firstName":"Rajnish","href":"http://stanfordhospital.org/profiles/Rajnish_Gupta","researchInterest":""},{"lastName":"Flynn","clinicalFocus":[],"appointments":[{"appointment":"MD Student, School of Medicine"},{"appointment":"Ph.D., Dean's Office"}],"primaryAppointment":"MD Student, School of Medicine","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=18677&type=small&showNoImage","displayName":"Ryan A Flynn","firstName":"Ryan","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Ryan_Flynn","researchInterest":"I'm interested in how non-coding RNAs mediate epigenetic changes during embryonic and cancer development."},{"lastName":"Wang","clinicalFocus":[{"focus":"Dermatology"},{"focus":"Complex Medical Dermatology"},{"focus":"Inpatient Dermatology"},{"focus":"Psoriasis"},{"focus":"Pruritus (Itching)"},{"focus":"Neuropathic/Neurogenic Dermatosis"}],"appointments":[{"appointment":"Instructor,Dermatology"},{"appointment":"Postdoctoral Research fellow, Dermatology"}],"primaryAppointment":"Instructor,Dermatology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=18079&type=small&showNoImage","displayName":"Kevin Wang","firstName":"Kevin","href":"http://stanfordhospital.org/profiles/Kevin_Wang","researchInterest":""},{"lastName":"Chu","clinicalFocus":[],"appointments":[{"appointment":"Ph.D., Dean's Office"},{"appointment":"Student Resident Asst,Academic and Residential Computing - Student Computing"}],"primaryAppointment":"Ph.D., Dean's Office","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=19664&type=small&showNoImage","displayName":"Ci Chu","firstName":"Ci","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Ci_Chu","researchInterest":"lncRNA and regulation of gene expression."},{"lastName":"Snyder","clinicalFocus":[],"appointments":[{"appointment":"Professor,Genetics"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Member,Child Health Research Institute"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Genetics","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=13465&type=small&showNoImage","displayName":"Michael Snyder","firstName":"Michael","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Michael_Snyder","researchInterest":"We are presently in an omics revolution in which genomes and other omes can be readily characterized. Our laboratory uses a variety of approaches to analyze genomes and regulatory networks. Our research focuses on yeast, an ideal model organism ideally suited to genetic analysis, and humans.\r\n\r\n1) Transcriptomes\r\nTo annotate genomes, we developed RNA sequencing for annotation the yeast and human transcriptomes. We discovered that the eukaryotic transcriptome is much more complex than previously"},{"lastName":"Giaccia","clinicalFocus":[],"appointments":[{"appointment":"Professor,Radiation Oncology - Radiation and Cancer Biology"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Professor (By courtesy),Obstetrics & Gynecology"},{"appointment":"Professor (By courtesy),Surgery"}],"primaryAppointment":"Professor,Radiation Oncology - Radiation and Cancer Biology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=4141&type=small&showNoImage","displayName":"Amato J. Giaccia","firstName":"Amato","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Amato_Giaccia","researchInterest":"During the last five years, we have identified several small molecules that kill VHL deficient renal cancer cells through a synthetic lethal screening approach. Another major interest of my laboratory is in identifying hypoxia-induced genes involved in invasion and metastases. We are also investigating how hypoxia regulates gene expression epigenetically."},{"lastName":"Chua","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Medicine - Endocrinology, Gerontology, & Metabolism"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Associate Professor,Medicine - Endocrinology, Gerontology, & Metabolism","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=6623&type=small&showNoImage","displayName":"Katrin Chua","firstName":"Katrin","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Katrin_Chua","researchInterest":"Our lab is interested in understanding molecular processes that underlie aging and age-associated pathologies in mammals.  We focus on a family of genes, the SIRTs, which regulate stress resistance and lifespan in lower organisms such as yeast, worms, and flies.  In mammals, we recently uncovered a number of ways in which SIRT factors may contribute to cellular and organismal aging by regulating resistance to various forms of stress.  We have now begun to characterize the molecular mechanisms b"},{"lastName":"Wong","clinicalFocus":[{"focus":"Dermatology"},{"focus":"Skin Cancer"},{"focus":"Teledermatology"}],"appointments":[{"appointment":"Clinical Assistant Professor,Dermatology"}],"primaryAppointment":"Clinical Assistant Professor,Dermatology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=7991&type=small&showNoImage","displayName":"David J. Wong, M.D., Ph.D.","firstName":"David","href":"http://stanfordhospital.org/profiles/David_Wong","researchInterest":"My research interest is focused on investigating the molecular networks that underlie cancer stem cells and designing therapies that selectively target these cells, thereby eliminating a cancer's potential for regrowth."},{"lastName":"Hu","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Obstetrics & Gynecology"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Associate Professor,Obstetrics & Gynecology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=10405&type=small&showNoImage","displayName":"Mickey Hu","firstName":"Mickey","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Mickey_Hu","researchInterest":""},{"lastName":"Brunet","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Genetics"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Associate Professor,Genetics","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=6012&type=small&showNoImage","displayName":"Anne Brunet","firstName":"Anne","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Anne_Brunet","researchInterest":"Our lab studies the molecular basis of longevity. We are interested in the mechanism of action of known longevity genes, including FOXO and SIRT, in the mammalian nervous system. We are particularly interested in the role of these longevity genes in neural stem cells. We are also discovering novel genes and processes involved in aging using two short-lived model systems, the invertebrate C. elegans and an extremely short-lived vertebrate, the African killifish N. furzeri."},{"lastName":"Boxer","clinicalFocus":[],"appointments":[{"appointment":"Ph.D., Biology (School of Humanities and Sciences)"}],"primaryAppointment":"Ph.D., Biology (School of Humanities and Sciences)","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=20204&type=small&showNoImage","displayName":"Lisa Boxer","firstName":"Lisa","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Lisa_Boxer","researchInterest":""},{"lastName":"Clarke","clinicalFocus":[{"focus":"Colorectal Cancer"},{"focus":"Oncology (Cancer)"},{"focus":"Medical Oncology"}],"appointments":[{"appointment":"Professor,Medicine - Oncology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Professor,Medicine - Oncology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=7126&type=small&showNoImage","displayName":"Michael F. Clarke, M.D.","firstName":"Michael","href":"http://stanfordhospital.org/profiles/Michael_Clarke","researchInterest":"Dr. Michael F. Clarke is the Associate Director of the Stanford Institute for Stem Cell and Regenerative Medicine.  In addition to his clinical duties in the division of Oncology, Dr. Clarke maintains a laboratory  focused on two areas of research: i) the control of self-renewal of normal stem cells and their malignant counterparts; and ii) the identification and characterization of cancer stem cells. A central issue in stem cell biology is to understand the mechanisms that regulate self-renewa"},{"lastName":"Cleary","clinicalFocus":[],"appointments":[{"appointment":"Professor,Pathology"},{"appointment":"Member,Child Health Research Institute"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Professor,Pediatrics"}],"primaryAppointment":"Professor,Pathology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=4506&type=small&showNoImage","displayName":"Michael Cleary","firstName":"Michael","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Michael_Cleary","researchInterest":"The role of oncoproteins in cancer and development; molecular and cellular biology of hematologic malignancies; targeted molecular therapies of cancer."},{"lastName":"Gomez","clinicalFocus":[],"appointments":[{"appointment":"Ph.D., Microbiology & Immunology"}],"primaryAppointment":"Ph.D., Microbiology & Immunology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=20206&type=small&showNoImage","displayName":"Antonio Gomez","firstName":"Jose","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Jose_Gomez","researchInterest":""},{"lastName":"Gozani","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Biology (School of Humanities and Sciences)"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Associate Professor,Biology (School of Humanities and Sciences)","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=6423&type=small&showNoImage","displayName":"Or Gozani","firstName":"Or","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Or_Gozani","researchInterest":"We study the molecular mechanisms by which chromatin-signaling networks effect nuclear and epigenetic programs, and how dysregulation of these pathways leads to disease.  Our work centers on the biology of lysine methylation, a principal chromatin-regulatory mechanism that directs epigenetic processes.  We study how lysine methylation events are generated, sensed, and transduced, and how these chemical marks integrate with other nuclear signaling systems to govern diverse cellular functions."},{"lastName":"Boxer","clinicalFocus":[{"focus":"Hematology"},{"focus":"Multiple Myeloma"},{"focus":"Multiple Myeloma - Medical Oncology"},{"focus":"Plasmacytoma"},{"focus":"Plasmacytoma - Hematology"},{"focus":"Plasmacytoma - Medical Oncology"}],"appointments":[{"appointment":"Professor,Medicine - Hematology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Professor,Medicine - Hematology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=4658&type=small&showNoImage","displayName":"Linda Boxer","firstName":"Linda","href":"http://stanfordhospital.org/profiles/Linda_Boxer","researchInterest":"Regulation of expression of oncogenes in normal and malignant hematologic cells."},{"lastName":"Tilgner","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Genetics"}],"primaryAppointment":"Postdoctoral Research fellow, Genetics","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=23131&type=small&showNoImage","displayName":"Hagen Tilgner","firstName":"Hagen","href":"http://med.stanford.edu/profiles/postdocs/researcher/Hagen_Tilgner","researchInterest":""},{"lastName":"Boyle","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Genetics"}],"primaryAppointment":"Postdoctoral Research fellow, Genetics","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=17416&type=small&showNoImage","displayName":"Alan Boyle","firstName":"Alan","href":"http://med.stanford.edu/profiles/postdocs/researcher/Alan_Boyle","researchInterest":""},{"lastName":"Bua","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Biology (School of Humanities and Sciences)"}],"primaryAppointment":"Postdoctoral Research fellow, Biology (School of Humanities and Sciences)","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=19834&type=small&showNoImage","displayName":"Dennis J Bua","firstName":"Dennis","href":"http://med.stanford.edu/profiles/postdocs/researcher/Dennis_Bua","researchInterest":""},{"lastName":"Maures","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Genetics"}],"primaryAppointment":"Postdoctoral Research fellow, Genetics","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=13311&type=small&showNoImage","displayName":"Travis J. Maures","firstName":"Travis","href":"http://med.stanford.edu/profiles/postdocs/researcher/Travis_Maures","researchInterest":""}]}