{"result":[{"lastName":"Hestrin","clinicalFocus":[],"appointments":[{"appointment":"Professor,Comparative Medicine"}],"primaryAppointment":"Professor,Comparative Medicine","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=4343&type=small&showNoImage","displayName":"Shaul Hestrin","firstName":"Shaul","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Shaul_Hestrin","researchInterest":"The main interest of my lab is to understand how the properties of neocortical neurons and the circuits they form give rise to cortical activity and function. Our approach includes recordings from multiple cells, calcium imaging, two-photon imaging and viral-based optogenetic methods to activate  cortical neurons as well as cortical afferents."},{"lastName":"Dolmetsch","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Neurobiology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Associate Professor,Neurobiology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=4040&type=small&showNoImage","displayName":"Ricardo Dolmetsch","firstName":"Ricardo","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Ricardo_Dolmetsch","researchInterest":"Our lab studies the underlying neurobiology of autism and other neuro-developmental disorders.  We are particularly interested in understanding how electrical activity and calcium signals control the development of the brain and how this is altered in children with autism spectrum disorders. We are also developing new tools to study and repair the developing brain."},{"lastName":"Meyer","clinicalFocus":[],"appointments":[{"appointment":"Professor,Chemical and Systems Biology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Chemical and Systems Biology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=4007&type=small&showNoImage","displayName":"Tobias Meyer","firstName":"Tobias","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Tobias_Meyer","researchInterest":"CELLULAR INFORMATION PROCESSING  The main problem in signal transduction is to understand how different receptor-stimuli specifically control diverse cell functions. We are using automated microscopy, live-cell fluorescent biosensors and perturbations of predicted signaling proteins to systematically dissect signaling networks.  This allows us to identify signaling modules and to elucidate and ultimately model the flow of cellular information."},{"lastName":"Lee","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Bioengineering"}],"primaryAppointment":"Postdoctoral Research fellow, Bioengineering","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=23467&type=small&showNoImage","displayName":"Soo Yeun Lee","firstName":"Soo Yeun","href":"http://med.stanford.edu/profiles/postdocs/researcher/Soo Yeun_Lee","researchInterest":""},{"lastName":"Luoma","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Neurosciences Institute"}],"primaryAppointment":"Postdoctoral Research fellow, Neurosciences Institute","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=24597&type=small&showNoImage","displayName":"Jessie Luoma","firstName":"Jessie","href":"http://med.stanford.edu/profiles/postdocs/researcher/Jessie_Luoma","researchInterest":""},{"lastName":"Berndt","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Bioengineering"}],"primaryAppointment":"Postdoctoral Research fellow, Bioengineering","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=24149&type=small&showNoImage","displayName":"Andre Berndt","firstName":"Andre","href":"http://med.stanford.edu/profiles/postdocs/researcher/Andre_Berndt","researchInterest":""},{"lastName":"Weiler","clinicalFocus":[],"appointments":[{"appointment":"Ph.D., Dean's Office"}],"primaryAppointment":"Ph.D., Dean's Office","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=19763&type=small&showNoImage","displayName":"Nicholas Weiler","firstName":"Nicholas","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Nicholas_Weiler","researchInterest":"I am interested in the structure of neocortex and the relation of circuit structure to neural activity and circuit function. My work in the Smith lab focuses on the development of array tomography methods to characterize and quantify populations of cortical synapses based on the diverse proteomic \"fingerprints\" of molecules characteristically expressed by different synapse types. My primary goal is to quantify the distribution of distinct synapse classes within columns of barrel cortex"},{"lastName":"Adhikari","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Bioengineering"}],"primaryAppointment":"Postdoctoral Research fellow, Bioengineering","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=21125&type=small&showNoImage","displayName":"Avishek Adhikari","firstName":"Avishek","href":"http://med.stanford.edu/profiles/postdocs/researcher/Avishek_Adhikari","researchInterest":""},{"lastName":"MacIver","clinicalFocus":[],"appointments":[{"appointment":"Professor (Research),Anesthesia"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor (Research),Anesthesia","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=4009&type=small&showNoImage","displayName":"M Bruce MacIver","firstName":"M","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/M_MacIver","researchInterest":"We study drug effects on the nervous system. Cellular, synaptic and molecular drug actions are investigated using electrophysiological and pharmacological tools in cortical/hippocampal brain slice preparations. We are also interested in mechanisms of neuronal integration and synchronization, especially related to patterns of EEG activity seen in vivo and in brain slices."},{"lastName":"de Lecea","clinicalFocus":[],"appointments":[{"appointment":"Professor,Psychiatry & Behavioral Science - Sleep Center"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Psychiatry & Behavioral Science - Sleep Center","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=7308&type=small&showNoImage","displayName":"Luis de Lecea","firstName":"Luis","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Luis_de Lecea","researchInterest":"My lab uses molecular, optogenetic, anatomical and behavioral methods to identify and manipulate the neuronal circuits underlying brain arousal, with particular attention to sleep and wakefulness transitions. We are also interested in the changes that occur in neuronal circuits in conditions of hyperarousal such as stress and drug addiction."},{"lastName":"Chen","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Psychiatry & Behavioral Science - Center for Interdisciplinary Brain Sciences Research"}],"primaryAppointment":"Associate Professor,Psychiatry & Behavioral Science - Center for Interdisciplinary Brain Sciences Research","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=20934&type=small&showNoImage","displayName":"Lu Chen","firstName":"Lu","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Lu_Chen","researchInterest":"What distinguishes us humans from other animals is our ability to undergo complex behavior. The synapses are the structural connection between neurons that mediates the communication between neurons, which underlies our various cognitive function. My research program aims to understand the cellular and molecular mechanisms that underlie synapse function during behavior in the developing and mature brain, and how synapse function is altered during mental retardation."},{"lastName":"Huguenard","clinicalFocus":[],"appointments":[{"appointment":"Professor,Neurology & Neurological Sciences"},{"appointment":"Member,Child Health Research Institute"},{"appointment":"Member,Bio-X"},{"appointment":"Professor (By courtesy),Molecular & Cellular Physiology"}],"primaryAppointment":"Professor,Neurology & Neurological Sciences","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=4124&type=small&showNoImage","displayName":"John Huguenard","firstName":"John","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/John_Huguenard","researchInterest":"We are interested in the neuronal mechanisms that underlie synchronous oscillatory activity in the thalamus, cortex and the massively interconnected thalamocortical system. Such oscillations are related to cognitive processes, normal sleep activities and certain forms of epilepsy. Our approach is an analysis of the discrete components (cells, synapses, microcircuits) that make up thalamic and cortical circuits, and reconstitution of components into in silico computational networks."},{"lastName":"Kerchner","clinicalFocus":[{"focus":"Alzheimer's Disease"},{"focus":"Mild Cognitive Impairment"},{"focus":"Dementia"},{"focus":"Behavioral Neurology"},{"focus":"Neurodegenerative Disease"},{"focus":"Neuropsychology"},{"focus":"Neurology"}],"appointments":[{"appointment":"Assistant Professor - Med Center Line,Neurology & Neurological Sciences"}],"primaryAppointment":"Assistant Professor - Med Center Line,Neurology & Neurological Sciences","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=15338&type=small&showNoImage","displayName":"Geoffrey Kerchner","firstName":"Geoffrey","href":"http://stanfordhospital.org/profiles/Geoffrey_Kerchner","researchInterest":"Dr. Kerchner is a behavioral neurologist who cares for patients with Alzheimer's disease and other age-related neurodegenerative illnesses. He studies the use of ultra-high field MRI and other advanced neuroimaging technologies to reveal how these diseases affect the microscopic structure and circuitry of the brain, with the intent of creating new strategies for early diagnosis. Dr. Kerchner also supervises the participation of patients in clinical trials for Alzheimer\u0092s disease."},{"lastName":"Graef","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Pathology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Assistant Professor,Pathology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=7247&type=small&showNoImage","displayName":"Isabella Graef","firstName":"Isabella","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Isabella_Graef","researchInterest":"We are interested in addressing questions in neuronal development and function by a combination of genetic, cell biological, biochemical and chemical approaches. \r\nThe main focus of our lab is centered around two topics: 1) the interface of signaling and gene regulation in neuronal development, with a focus on calcineurin-NFAT signaling; 2) the development of small molecules, which interfere with protein-protein interactions underlying neurodegenerative diseases."},{"lastName":"Ding","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Neurology & Neurological Sciences"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Assistant Professor,Neurology & Neurological Sciences","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=32293&type=small&showNoImage","displayName":"Jun Ding","firstName":"Jun","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Jun_Ding","researchInterest":"Neural circuits of movement control in health and movement disorders"},{"lastName":"Prince","clinicalFocus":[],"appointments":[{"appointment":"Professor,Neurology & Neurological Sciences"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Neurology & Neurological Sciences","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=4531&type=small&showNoImage","displayName":"David Prince","firstName":"David","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/David_Prince","researchInterest":"Experiments examine \r\n1)intrinsic properties of neuronal membranes; actions of neurotransmitters that regulate neocortical and thalamic excitability\r\n2) chronic epileptogenesis following cortical injury; changes in intracortical connectivity and receptors; \r\n3) effects of early injury and activity on cortical development/maldevelopment Electrophysiological, anatomical and pharmacological techniques employed.\r\n4. prophylaxis of postraumatic epilepsy\r\n5. Neocortical interneuronal function/modulation"},{"lastName":"Boahen","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Bioengineering"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Associate Professor,Bioengineering","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=7204&type=small&showNoImage","displayName":"Kwabena Boahen","firstName":"Kwabena","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Kwabena_Boahen","researchInterest":""},{"lastName":"Henderson","clinicalFocus":[{"focus":"Neurological Surgery"},{"focus":"Movement Disorders"},{"focus":"Pain"}],"appointments":[{"appointment":"Associate Professor - Med Center Line,Neurosurgery"},{"appointment":"Associate Professor - Med Center Line (By courtesy),Neurology & Neurological Sciences"}],"primaryAppointment":"Associate Professor - Med Center Line,Neurosurgery","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=6330&type=small&showNoImage","displayName":"Jaimie Henderson","firstName":"Jaimie","href":"http://stanfordhospital.org/profiles/Jaimie_Henderson","researchInterest":"My research interests encompass several areas of stereotactic and functional neurosurgery, including frameless stereotactic approaches for therapy delivery to deep brain nuclei; deformable patient-specific atlases for targeting brain structures; cortical physiology and its relationship to normal and pathological movement; neural prostheses; and the development of novel neuromodulatory techniques for the treatment of movement disorders, pain, and other neurological diseases."},{"lastName":"Monje-Deisseroth","clinicalFocus":[{"focus":"Neurology"}],"appointments":[{"appointment":"Assistant Professor,Neurology & Neurological Sciences"},{"appointment":"Member,Child Health Research Institute"},{"appointment":"Member,Bio-X"},{"appointment":"Assistant Professor (By courtesy),Neurosurgery"},{"appointment":"Assistant Professor (By courtesy),Pediatrics"}],"primaryAppointment":"Assistant Professor,Neurology & Neurological Sciences","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=18279&type=small&showNoImage","displayName":"Michelle Monje","firstName":"Michelle","href":"http://stanfordhospital.org/profiles/Michelle_Monje-Deisseroth","researchInterest":"The Monje Lab studies the molecular and cellular mechanisms of postnatal neurodevelopment. This includes microenvironmental influences on neural precursor cell fate choice in normal neurodevelopment and in disease states."},{"lastName":"Garner","clinicalFocus":[],"appointments":[{"appointment":"Professor,Psychiatry & Behavioral Science - Psychiatry/Neuroscience/MSLS"},{"appointment":"Member,Bio-X"},{"appointment":"Professor (By courtesy),Neurology & Neurological Sciences"}],"primaryAppointment":"Professor,Psychiatry & Behavioral Science - Psychiatry/Neuroscience/MSLS","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=3890&type=small&showNoImage","displayName":"Craig C. Garner","firstName":"Craig","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Craig_Garner","researchInterest":"Our laboratory is studying synapse formation, stability and elimination at a variety of levels, e.g. from molecules to behavior.  A primary focus of the lab is to understanding the role that individual molecules play in the assembly and function of synaptic junctions.  In addition we evaluating a variety of potential treatments for cognitive impairment in Down syndrome in part by assessing the impact specific drugs on cognitive function in mouse models of Down syndrome."},{"lastName":"Mourrain","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor (Research),Psychiatry & Behavioral Science - Sleep Center"}],"primaryAppointment":"Associate Professor (Research),Psychiatry & Behavioral Science - Sleep Center","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=24313&type=small&showNoImage","displayName":"Philippe Mourrain","firstName":"Philippe","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Philippe_Mourrain","researchInterest":""},{"lastName":"McConnell","clinicalFocus":[],"appointments":[{"appointment":"Professor,Biology (School of Humanities and Sciences)"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Biology (School of Humanities and Sciences)","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=5928&type=small&showNoImage","displayName":"Susan K. McConnell","firstName":"Susan","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Susan_McConnell","researchInterest":"The McConnell Lab studies the cellular and molecular mechanisms that underlie the development of the mammalian cerebral cortex.  Our work focuses on the earliest events that pattern the developing forebrain, enable neural progenitors to divide asymmetrically to generate young neurons, propel the migration of postmitotic neurons outward into their final positions, and sculpt the fates and phenotypes of the neurons as they differentiate."},{"lastName":"Malenka","clinicalFocus":[],"appointments":[{"appointment":"Professor,Psychiatry & Behavioral Science - Psychiatry/Neuroscience/MSLS"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Psychiatry & Behavioral Science - Psychiatry/Neuroscience/MSLS","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=4670&type=small&showNoImage","displayName":"Robert Malenka","firstName":"Robert","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Robert_Malenka","researchInterest":"Long-lasting changes in synaptic strength are important for the modification of neural circuits by experience. A major goal of my laboratory is to elucidate the molecular events that trigger various forms of synaptic plasticity and the modifications in synaptic proteins that are responsible for the changes in synaptic efficacy."}]}