{"result":[{"lastName":"Ruoss","clinicalFocus":[{"focus":"Critical Care Medicine"},{"focus":"Pulmonology (Lung) and Critical Care "},{"focus":"Internal Medicine"}],"appointments":[{"appointment":"Professor - Med Center Line,Medicine - Pulmonary & Critical Care Medicine"}],"primaryAppointment":"Professor - Med Center Line,Medicine - Pulmonary & Critical Care Medicine","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=4241&type=small&showNoImage","displayName":"Stephen Ruoss","firstName":"Stephen","href":"http://stanfordhospital.org/profiles/Stephen_Ruoss","researchInterest":"We have an active collaborative project examining basic and clinical aspects of non-tuberculous mycobacterial lung infection in non-immune compromised adults. Studies have examined possible cellular immune mechanisms for increased susceptibility to these infections, and are also investigating aspects of optimal diagnosis and treatment. In addition, a clinical and translational research program is investigating the causes and genetic factors underlying the evolution of bronchiectasis."},{"lastName":"Rosen","clinicalFocus":[{"focus":"Pulmonology (Lung) and Critical Care "},{"focus":"Pulmonary Disease"}],"appointments":[{"appointment":"Associate Professor,Medicine - Pulmonary & Critical Care Medicine"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Associate Professor,Medicine - Pulmonary & Critical Care Medicine","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=4245&type=small&showNoImage","displayName":"Glenn Rosen","firstName":"Glenn","href":"http://stanfordhospital.org/profiles/Glenn_Rosen","researchInterest":"Our laboratory examines apoptotic and cell cycle pathways in cancer and lung disease. We have identified a novel cell cycle protein which regulates cell cycle progression in immune cells and the lung.  We are also studying signaling pathways that regulate cancer cell growth and metastasis."},{"lastName":"Graef","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Pathology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Assistant Professor,Pathology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=7247&type=small&showNoImage","displayName":"Isabella Graef","firstName":"Isabella","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Isabella_Graef","researchInterest":"We are interested in addressing questions in neuronal development and function by a combination of genetic, cell biological, biochemical and chemical approaches. \r\nThe main focus of our lab is centered around two topics: 1) the interface of signaling and gene regulation in neuronal development, with a focus on calcineurin-NFAT signaling; 2) the development of small molecules, which interfere with protein-protein interactions underlying neurodegenerative diseases."},{"lastName":"Gardner","clinicalFocus":[],"appointments":[{"appointment":"Professor,Medicine - Clinical Pharmacology"}],"primaryAppointment":"Professor,Medicine - Clinical Pharmacology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=4500&type=small&showNoImage","displayName":"Phyllis Gardner","firstName":"Phyllis","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Phyllis_Gardner","researchInterest":"Ion channels and signal transduction;  patch clamp and fluorometric analysis; cell and molecular biology; cystic fibrosis gene therapy."},{"lastName":"de Jesus Perez","clinicalFocus":[{"focus":"Pulmonary Disease"},{"focus":"Pulmonary Hypertension"},{"focus":"drug induced pulmonary hypertension"}],"appointments":[{"appointment":"Assistant Professor,Medicine - Pulmonary & Critical Care Medicine"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Assistant Professor,Medicine - Pulmonary & Critical Care Medicine","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=7827&type=small&showNoImage","displayName":"Vinicio de Jesus Perez MD","firstName":"Vinicio","href":"http://stanfordhospital.org/profiles/Vinicio_de Jesus Perez","researchInterest":"My work is aimed at understanding the molecular mechanisms involved in the development and progression of pulmonary arterial hypertension (PAH).   I am interested in understanding the role that the BMP  and Wnt pathways play in regulating functions of pulmonary endothelial and smooth muscle cells both in health and disease."},{"lastName":"Hu","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Obstetrics & Gynecology"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Associate Professor,Obstetrics & Gynecology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=10405&type=small&showNoImage","displayName":"Mickey Hu","firstName":"Mickey","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Mickey_Hu","researchInterest":""},{"lastName":"Utz","clinicalFocus":[{"focus":"Immunology and Rheumatology"},{"focus":"Rheumatology"}],"appointments":[{"appointment":"Professor,Medicine - Immunology & Rheumatology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Medicine - Immunology & Rheumatology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=4001&type=small&showNoImage","displayName":"Paul Utz","firstName":"Paul","href":"http://stanfordhospital.org/profiles/Paul_Utz","researchInterest":"The long-term research goal of Dr. Utz\u0092s laboratory is (1) to develop a better understanding of the pathogenic mechanisms underlying systemic lupus erythematosus (SLE) and other autoimmune diseases by exploring signaling pathways that are activated during apoptosis; and (2) to better understand the complicated process of programmed cell death."},{"lastName":"Peltz","clinicalFocus":[],"appointments":[{"appointment":"Professor,Anesthesia"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Anesthesia","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=8527&type=small&showNoImage","displayName":"Gary Peltz","firstName":"Gary","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Gary_Peltz","researchInterest":"The laboratory develops and uses state of the art genomic methods to identify genetic factors affecting disease susceptibility, and to translate these findings into new treatments. We have developed a more efficient method for performing mouse genetic analysis, which has been used to analyze the genetic basis for 16 different biomedical traits. We are developing novel methods, and have developed a novel experimental platform that replaces mouse liver with functioning human liver tissue."},{"lastName":"Chu","clinicalFocus":[{"focus":"Oncology"}],"appointments":[{"appointment":"Professor,Medicine - Oncology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Professor,Biochemistry"}],"primaryAppointment":"Professor,Medicine - Oncology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=4149&type=small&showNoImage","displayName":"Gilbert Chu","firstName":"Gilbert","href":"http://stanfordhospital.org/profiles/Gilbert_Chu","researchInterest":"Our laboratory focuses on understanding how cells respond to DNA damage. Our research currently involves areas that interact with each other: repair of radiation damage, and transcriptional responses to DNA damage."},{"lastName":"Chang","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Medicine - Cardiovascular Medicine"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Child Health Research Institute"}],"primaryAppointment":"Associate Professor,Medicine - Cardiovascular Medicine","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=6387&type=small&showNoImage","displayName":"Ching-Pin Chang","firstName":"Ching-Pin","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Ching-Pin_Chang","researchInterest":"The ultimate goal of my laboratory is to define the molecular mechanisms underlying cardiovascular development and disease and translate the bench findings to clinical applications. One objective is to understand how the major types of cardiac cells (endocardial, myocardial, epicardial and neural crest cells) interact with each other to generate heart tissues. We are interested in chromatin regulation, transcriptional and signaling events that coordinate their interactions and assembly into hea"},{"lastName":"Spiekerkoetter","clinicalFocus":[{"focus":"Pulmonary Medicine"},{"focus":"Pulmonary Hypertension"}],"appointments":[{"appointment":"Assistant Professor,Medicine - Pulmonary & Critical Care Medicine"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Assistant Professor,Medicine - Pulmonary & Critical Care Medicine","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=14775&type=small&showNoImage","displayName":"Edda Spiekerkoetter","firstName":"Edda","href":"http://stanfordhospital.org/profiles/Edda_Spiekerkoetter","researchInterest":""},{"lastName":"Giaccia","clinicalFocus":[],"appointments":[{"appointment":"Professor,Radiation Oncology - Radiation and Cancer Biology"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Professor (By courtesy),Obstetrics & Gynecology"},{"appointment":"Professor (By courtesy),Surgery"}],"primaryAppointment":"Professor,Radiation Oncology - Radiation and Cancer Biology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=4141&type=small&showNoImage","displayName":"Amato J. Giaccia","firstName":"Amato","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Amato_Giaccia","researchInterest":"During the last five years, we have identified several small molecules that kill VHL deficient renal cancer cells through a synthetic lethal screening approach. Another major interest of my laboratory is in identifying hypoxia-induced genes involved in invasion and metastases. We are also investigating how hypoxia regulates gene expression epigenetically."},{"lastName":"Boxer","clinicalFocus":[{"focus":"Hematology"},{"focus":"Multiple Myeloma"},{"focus":"Multiple Myeloma - Medical Oncology"},{"focus":"Plasmacytoma"},{"focus":"Plasmacytoma - Hematology"},{"focus":"Plasmacytoma - Medical Oncology"}],"appointments":[{"appointment":"Professor,Medicine - Hematology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Professor,Medicine - Hematology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=4658&type=small&showNoImage","displayName":"Linda Boxer","firstName":"Linda","href":"http://stanfordhospital.org/profiles/Linda_Boxer","researchInterest":"Regulation of expression of oncogenes in normal and malignant hematologic cells."},{"lastName":"Leung","clinicalFocus":[{"focus":"Hematology"}],"appointments":[{"appointment":"Professor,Medicine - Hematology"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Professor,Medicine - Hematology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=4150&type=small&showNoImage","displayName":"Lawrence Leung","firstName":"Lawrence","href":"http://stanfordhospital.org/profiles/Lawrence_Leung","researchInterest":"Our long term interest is to have a better understanding of the natural antithrombotic pathways and the pathophysiology of vascular thrombosis. We have focused on thrombin, the key enzyme in the blood clotting cascade.Our goal is to develop new antithrombotic agents and devise new diagnostic tests for vascular thrombotic disorders."},{"lastName":"Shah","clinicalFocus":[{"focus":"Pediatrics"},{"focus":"Pediatric Endocrinology & Diabetes"}],"appointments":[{"appointment":"Clinical Instructor,Pediatrics - Endocrinology and Diabetes"}],"primaryAppointment":"Clinical Instructor,Pediatrics - Endocrinology and Diabetes","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=17622&type=small&showNoImage","displayName":"Sejal Shah","firstName":"Sejal","href":"http://stanfordhospital.org/profiles/Sejal_Shah","researchInterest":"My primary research interest is evaluating whether vitamin D supplementation can positively affect consequences of the metabolic syndrome in overweight and obese adolescents.  Other research interests include evaluating the efficacy and biochemical profiles of various types of estrogen replacement in adolescent females."},{"lastName":"Winslow","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Genetics"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Assistant Professor,Genetics","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=24603&type=small&showNoImage","displayName":"Monte Winslow","firstName":"Monte","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Monte_Winslow","researchInterest":"Our laboratory uses genome-wide methods to uncover alterations that drive cancer progression and metastasis in genetically-engineered mouse models of human cancers. We combine cell-culture based mechanistic studies with our ability to alter pathways of interest during tumor progression in vivo to better understand each step of metastatic spread and to uncover the therapeutic vulnerabilities of advanced cancer cells."},{"lastName":"Zamanian","clinicalFocus":[{"focus":"Pulmonary Hypertension"},{"focus":"Pulmonology (Lung) and Critical Care "},{"focus":"Pulmonary Medicine"}],"appointments":[{"appointment":"Assistant Professor - Med Center Line,Medicine - Pulmonary & Critical Care Medicine"}],"primaryAppointment":"Assistant Professor - Med Center Line,Medicine - Pulmonary & Critical Care Medicine","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=7572&type=small&showNoImage","displayName":"Roham Zamanian","firstName":"Roham","href":"http://stanfordhospital.org/profiles/Roham_Zamanian","researchInterest":"1. The Utility of S100A4/Mts1 as a Biomarker in Pulmonary Arterial Hypertension (PAH).\r\n\r\n2. Prevalence and Treatment of Insulin Resistance in PAH.\r\n\r\n3. The Effect of EGF-Receptor Blockade and Elastase Inhibitor on Pulmonary Arteries of Patients with PAH.\r\n\r\n4. Characterization of Pulmonary Arteries in Patients with Idiopathic and Secondary PAH by Wedge Angiography.\r\n\r\n5. The Optimal Angle for Angiographic Evaluation of the Left Pulmonary Artery in Patients with PAH."},{"lastName":"Meyer","clinicalFocus":[],"appointments":[{"appointment":"Professor,Chemical and Systems Biology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Chemical and Systems Biology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=4007&type=small&showNoImage","displayName":"Tobias Meyer","firstName":"Tobias","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Tobias_Meyer","researchInterest":"CELLULAR INFORMATION PROCESSING  The main problem in signal transduction is to understand how different receptor-stimuli specifically control diverse cell functions. We are using automated microscopy, live-cell fluorescent biosensors and perturbations of predicted signaling proteins to systematically dissect signaling networks.  This allows us to identify signaling modules and to elucidate and ultimately model the flow of cellular information."},{"lastName":"Sun","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Urology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Associate Professor,Genetics"}],"primaryAppointment":"Associate Professor,Urology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=4402&type=small&showNoImage","displayName":"Zijie Sun","firstName":"Zijie","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Zijie_Sun","researchInterest":"My lab focuses on understanding the molecular mechanism of transcription factors that govern the transformation of normal mammalian cells to a neoplastic state. We are especially interested in the action of the nuclear hormone receptors and the interactions between the receptors and other signaling pathways in related human disorders."},{"lastName":"Le","clinicalFocus":[{"focus":"Pediatric Critical Care Medicine"},{"focus":"Pediatric Intensive Care"}],"appointments":[{"appointment":"Clinical Assistant Professor,Pediatrics - Critical Care"}],"primaryAppointment":"Clinical Assistant Professor,Pediatrics - Critical Care","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=14193&type=small&showNoImage","displayName":"Truc Le","firstName":"Truc","href":"http://stanfordhospital.org/profiles/Truc_Le","researchInterest":"My research interest is studying genetic polymorphisms that affect glutathione synthesis and metabolism and their effects on clinical disease and oxidative injury."},{"lastName":"O'Brodovich","clinicalFocus":[{"focus":"Pediatric Pulmonary"},{"focus":"Pulmonary Medicine/Cystic Fibrosis, Pediatric"}],"appointments":[{"appointment":"Professor,Pediatrics"},{"appointment":"Member,Child Health Research Institute"}],"primaryAppointment":"Professor,Pediatrics","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=8414&type=small&showNoImage","displayName":"Hugh O'Brodovich","firstName":"Hugh","href":"http://stanfordhospital.org/profiles/Hugh_O'Brodovich","researchInterest":"Clinical: \r\nPulmonary edema, acute respiratory distress syndromes (ARDS), hyaline membrane disease (HMD), bronchopulmonary dysplasia (BPD)\r\n\r\nBasic Science: \r\nLung epithelial sodium transport\r\nGenetic influences on the development of BPD"},{"lastName":"Ruiz-Lozano","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor (Research),Pediatrics - Cardiology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Child Health Research Institute"}],"primaryAppointment":"Associate Professor (Research),Pediatrics - Cardiology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=18359&type=small&showNoImage","displayName":"Pilar Ruiz-Lozano, Ph.D.","firstName":"Pilar","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Pilar_Ruiz-Lozano","researchInterest":"Cardiac development and repair"},{"lastName":"Gilly","clinicalFocus":[],"appointments":[{"appointment":"Professor,Biology (School of Humanities and Sciences)"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Biology (School of Humanities and Sciences)","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=6223&type=small&showNoImage","displayName":"William Gilly","firstName":"William","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/William_Gilly","researchInterest":""}]}