{"result":[{"lastName":"Bauer","clinicalFocus":[],"appointments":[{"appointment":"Emeritus Faculty, Acad Council,Dermatology"}],"primaryAppointment":"Emeritus Faculty, Acad Council,Dermatology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=4177&type=small&showNoImage","displayName":"Eugene Bauer","firstName":"Eugene","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Eugene_Bauer","researchInterest":"Defining the role of matrix metalloproteinases in connective tissue remodeling of the skin.\u000bDefining the macromolecular structures of the cutaneous basement membrane zone.\u000bDeveloping methods for delivery of extracutaneous gene therapy in epidermolysis bullosa."},{"lastName":"Hu","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Obstetrics & Gynecology"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Associate Professor,Obstetrics & Gynecology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=10405&type=small&showNoImage","displayName":"Mickey Hu","firstName":"Mickey","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Mickey_Hu","researchInterest":""},{"lastName":"Giaccia","clinicalFocus":[],"appointments":[{"appointment":"Professor,Radiation Oncology - Radiation and Cancer Biology"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Professor (By courtesy),Obstetrics & Gynecology"},{"appointment":"Professor (By courtesy),Surgery"}],"primaryAppointment":"Professor,Radiation Oncology - Radiation and Cancer Biology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=4141&type=small&showNoImage","displayName":"Amato J. Giaccia","firstName":"Amato","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Amato_Giaccia","researchInterest":"During the last five years, we have identified several small molecules that kill VHL deficient renal cancer cells through a synthetic lethal screening approach. Another major interest of my laboratory is in identifying hypoxia-induced genes involved in invasion and metastases. We are also investigating how hypoxia regulates gene expression epigenetically."},{"lastName":"Ko","clinicalFocus":[],"appointments":[{"appointment":"MD Student, School of Medicine"}],"primaryAppointment":"MD Student, School of Medicine","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=17973&type=small&showNoImage","displayName":"Myung Ko","firstName":"Myung","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Myung_Ko","researchInterest":""},{"lastName":"Marques","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Pediatrics"}],"primaryAppointment":"Postdoctoral Research fellow, Pediatrics","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=19508&type=small&showNoImage","displayName":"Michelle Marques","firstName":"Michelle","href":"http://med.stanford.edu/profiles/postdocs/researcher/Michelle_Marques","researchInterest":""},{"lastName":"Wong","clinicalFocus":[],"appointments":[{"appointment":"Professor,Neurosurgery"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Professor,Neurosurgery","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=7143&type=small&showNoImage","displayName":"Albert J. Wong, M.D.","firstName":"Albert","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Albert_Wong","researchInterest":"Our goal is to define targets for cancer therapeutics by identifying alterations in signal transduction proteins. We first identified a naturally occurring mutant EGF receptor (EGFRvIII) and then delineated its unique signal transduction pathway. This work led to the identification of Gab1 followed by the discovery that JNK is constitutively active in tumors. We intiated using altered proteins as the target for vaccination, where an EGFRvIII based vaccine appears to be highly effective."},{"lastName":"Utz","clinicalFocus":[{"focus":"Immunology and Rheumatology"},{"focus":"Rheumatology"}],"appointments":[{"appointment":"Professor,Medicine - Immunology & Rheumatology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Medicine - Immunology & Rheumatology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=4001&type=small&showNoImage","displayName":"Paul Utz","firstName":"Paul","href":"http://stanfordhospital.org/profiles/Paul_Utz","researchInterest":"The long-term research goal of Dr. Utz\u0092s laboratory is (1) to develop a better understanding of the pathogenic mechanisms underlying systemic lupus erythematosus (SLE) and other autoimmune diseases by exploring signaling pathways that are activated during apoptosis; and (2) to better understand the complicated process of programmed cell death."},{"lastName":"Lee","clinicalFocus":[],"appointments":[{"appointment":"Basic Life Science Research Associate,Developmental Biology"}],"primaryAppointment":"Basic Life Science Research Associate,Developmental Biology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=9203&type=small&showNoImage","displayName":"Jonghyeob Lee","firstName":"Jonghyeob","href":"http://stanfordhospital.org/profiles/Jonghyeob_Lee","researchInterest":""},{"lastName":"Lane","clinicalFocus":[{"focus":"Pediatric Dermatology"},{"focus":"Ethical Issues in Pediatric Dermatology"}],"appointments":[{"appointment":"Emeritus (Active) Professor,Dermatology"},{"appointment":"Emeritus Faculty-Med Ctr Line,Retiree"},{"appointment":"Member,Child Health Research Institute"}],"primaryAppointment":"Emeritus (Active) Professor,Dermatology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=4126&type=small&showNoImage","displayName":"Alfred Lane","firstName":"Alfred","href":"http://stanfordhospital.org/profiles/Alfred_Lane","researchInterest":"Developing gene therapy for genetic skin diseases is my major focus. Prior to that, we are developing methods to give effective and efficient care to infants with rare and disabling genetic skin diseases including epidermolysis bullosa and ichthyosis as well as infants and children with unusual and difficult to manage vascular malformations. I am also interested in clinical studies within the NICU protecting premature infants\u0092 skin and clinical studies in children with common skin diseases."},{"lastName":"Amieva","clinicalFocus":[{"focus":"Infectious Diseases, Pediatric"},{"focus":"Pediatric Infectious Disease"}],"appointments":[{"appointment":"Associate Professor,Pediatrics - Infectious Diseases"},{"appointment":"Associate Professor,Microbiology & Immunology"}],"primaryAppointment":"Associate Professor,Pediatrics - Infectious Diseases","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=6150&type=small&showNoImage","displayName":"Manuel Amieva","firstName":"Manuel","href":"http://stanfordhospital.org/profiles/Manuel_Amieva","researchInterest":"My laboratory studies the strategies pathogens utilize to colonize and subvert the epithelial barrier. We have focused on the epithelial junctions as a target for bacterial pathogens, since the cell-cell junctions serve as both a barrier to infection and also a major control site for epithelial function. In particular, we are interested in how the gastric pathogen Helicobater pylori may cause cancer by interfering with cell signaling at the epithelial junctions. We are also studying how variou"},{"lastName":"Kim","clinicalFocus":[{"focus":"Cancer- cutaneous oncology"},{"focus":"Melanocytic neoplasia"},{"focus":"Dermatopathology"}],"appointments":[{"appointment":"Assistant Professor - Med Center Line,Pathology"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Assistant Professor - Med Center Line,Dermatology"}],"primaryAppointment":"Assistant Professor - Med Center Line,Pathology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=8622&type=small&showNoImage","displayName":"Jinah Kim","firstName":"Jinah","href":"http://stanfordhospital.org/profiles/Jinah_Kim","researchInterest":""},{"lastName":"Karasek","clinicalFocus":[],"appointments":[{"appointment":"Emeritus Faculty, Acad Council,Dermatology"}],"primaryAppointment":"Emeritus Faculty, Acad Council,Dermatology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=6333&type=small&showNoImage","displayName":"Marvin Karasek","firstName":"Marvin","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Marvin_Karasek","researchInterest":""},{"lastName":"Meyer","clinicalFocus":[],"appointments":[{"appointment":"Professor,Chemical and Systems Biology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Chemical and Systems Biology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=4007&type=small&showNoImage","displayName":"Tobias Meyer","firstName":"Tobias","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Tobias_Meyer","researchInterest":"CELLULAR INFORMATION PROCESSING The main problem in signal transduction is to understand how different receptor-stimuli specifically control diverse cell functions. We are using automated microscopy, live-cell fluorescent biosensors and perturbations of predicted signaling proteins to systematically dissect signaling networks. This allows us to identify signaling modules and to elucidate and ultimately model the flow of cellular information."},{"lastName":"Sunwoo","clinicalFocus":[{"focus":"Thyroid Neoplasms"},{"focus":"Melanoma"},{"focus":"Parathyroid Neoplasms"},{"focus":"Tongue Neoplasms"},{"focus":"Otolaryngology - Head & Neck Surgery (Ear, Nose and Throat)"},{"focus":"Otolaryngology"},{"focus":"Thyroid Nodule"},{"focus":"Parotid Neoplasms"},{"focus":"Tonsillar Neoplasms"},{"focus":"Pharynx Neoplasms"},{"focus":"Cancer of the Pharynx"},{"focus":"Cancer of the Larynx"},{"focus":"Cancer Stem Cells"},{"focus":"Cancer of Mouth"},{"focus":"Cancer of Neck"},{"focus":"Cancer of the Nasopharynx"},{"focus":"Cancer of Oropharnyx"},{"focus":"Cancer of the Parotid"},{"focus":"Cancer of the Salivary Gland"}],"appointments":[{"appointment":"Assistant Professor,Otolaryngology (Head and Neck Surgery)"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Assistant Professor,Otolaryngology (Head and Neck Surgery)","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=8588&type=small&showNoImage","displayName":"John B. Sunwoo","firstName":"John","href":"http://stanfordhospital.org/profiles/John_Sunwoo","researchInterest":"My laboratory is focused on two primary areas of research: (1) the immune response to head and neck cancer and to a tumorigenic population of cells within these malignancies called cancer stem cells; (2) the developmental programs of a special lymphocyte population involved in innate immunity called natural killer (NK) cells."},{"lastName":"Rosen","clinicalFocus":[{"focus":"Pulmonology (Lung) and Critical Care "},{"focus":"Pulmonary Disease"}],"appointments":[{"appointment":"Associate Professor,Medicine - Pulmonary & Critical Care Medicine"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Associate Professor,Medicine - Pulmonary & Critical Care Medicine","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=4245&type=small&showNoImage","displayName":"Glenn Rosen","firstName":"Glenn","href":"http://stanfordhospital.org/profiles/Glenn_Rosen","researchInterest":"Our laboratory examines apoptotic and cell cycle pathways in cancer and lung disease. We have identified a novel cell cycle protein which regulates cell cycle progression in immune cells and the lung. We are also studying signaling pathways that regulate cancer cell growth and metastasis."},{"lastName":"Michie","clinicalFocus":[{"focus":"Anatomic Pathology"},{"focus":"Pathology and Laboratory Medicine"}],"appointments":[{"appointment":"Professor,Pathology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Pathology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=4707&type=small&showNoImage","displayName":"Sara Michie","firstName":"Sara","href":"http://stanfordhospital.org/profiles/Sara_Michie","researchInterest":"Lymphocyte/endothelial cell adhesion mechanisms involved in lymphocyte migration to sites of inflammation; regulation of expression of endothelial cell adhesion molecules."},{"lastName":"Gurtner","clinicalFocus":[{"focus":"Plastic Surgery"},{"focus":"Plastic & Recon Surgery"}],"appointments":[{"appointment":"Professor - Med Center Line,Surgery - Plastic & Reconstructive Surgery"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Professor - Med Center Line (By courtesy),Materials Science and Engineering - Engineering Materials Science"}],"primaryAppointment":"Professor - Med Center Line,Surgery - Plastic & Reconstructive Surgery","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=6890&type=small&showNoImage","displayName":"Geoffrey Gurtner","firstName":"Geoffrey","href":"http://stanfordhospital.org/profiles/Geoffrey_Gurtner","researchInterest":"Geoffrey Gurtner's Lab is interested in understanding the mecahnism of new blood vessel growth following injury and how pathways of tissue regeneration and fibrosis interact in wound healing."},{"lastName":"Rouse","clinicalFocus":[],"appointments":[{"appointment":"Professor - Med Center Line,Pathology"}],"primaryAppointment":"Professor - Med Center Line,Pathology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=4491&type=small&showNoImage","displayName":"Robert V Rouse","firstName":"Robert","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Robert_Rouse","researchInterest":"My recent research efforts are currently focused in the field of applications of immunohistology to the diagnosis of human neoplasms. This work is predominantly aimed at characterizing markers for the identification of non-lymphoid neoplasms and at establishing criteria for their evaluation in diagnostic situations."},{"lastName":"Habib","clinicalFocus":[],"appointments":[{"appointment":"Basic Life Science Research Associate,Developmental Biology"}],"primaryAppointment":"Basic Life Science Research Associate,Developmental Biology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=9590&type=small&showNoImage","displayName":"Shukry Habib","firstName":"Shukry","href":"http://stanfordhospital.org/profiles/Shukry_Habib","researchInterest":"Can External Cues Induce Asymmetric Division of Stem cells?"},{"lastName":"Yang","clinicalFocus":[{"focus":"General Surgery"}],"appointments":[{"appointment":"Associate Professor - Med Center Line,Surgery - General Surgery"}],"primaryAppointment":"Associate Professor - Med Center Line,Surgery - General Surgery","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=6176&type=small&showNoImage","displayName":"George Yang","firstName":"George","href":"http://stanfordhospital.org/profiles/George_Yang","researchInterest":"Our laboratory studies the role of cellular stress pathways in the response to injury, particularly wound healing and fracture healing."},{"lastName":"Cochran","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Bioengineering"},{"appointment":"Member,Child Health Research Institute"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Member,Bio-X"},{"appointment":"Associate Professor (By courtesy),Chemical Engineering"}],"primaryAppointment":"Associate Professor,Bioengineering","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=6393&type=small&showNoImage","displayName":"Jennifer R. Cochran","firstName":"Jennifer","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Jennifer_Cochran","researchInterest":"Molecular Bioengineering, Protein Biochemistry and Biotechnology, Cell and Tissue Engineering, Molecular Imaging"},{"lastName":"Woo","clinicalFocus":[],"appointments":[{"appointment":"Basic Life Science Research Associate,Dermatology"}],"primaryAppointment":"Basic Life Science Research Associate,Dermatology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=9651&type=small&showNoImage","displayName":"Wei-Meng Woo","firstName":"Wei","href":"http://stanfordhospital.org/profiles/Wei_Woo","researchInterest":""},{"lastName":"Atwood","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Dermatology"}],"primaryAppointment":"Postdoctoral Research fellow, Dermatology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=10356&type=small&showNoImage","displayName":"Scott Atwood","firstName":"Scott","href":"http://med.stanford.edu/profiles/postdocs/researcher/Scott_Atwood","researchInterest":"My research focus is on protein kinase regulation of primary cilia-mediated signaling, skin and hair follicle development, and epithelial tumor progression. My work has discovered novel roles of kinases in neural stem cell self-renewal and differentiation, primary cilia structure and signaling, hair follicle cycling, and basal cell carcinoma progression. How kinases achieve these diverse functions are an ongoing area of investigation."}]}