{"result":[{"lastName":"Nusse","clinicalFocus":[],"appointments":[{"appointment":"Professor,Developmental Biology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Professor,Developmental Biology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=4280&type=small&showNoImage","displayName":"Roeland Nusse","firstName":"Roeland","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Roeland_Nusse","researchInterest":"Our laboratory studies Wnt signaling in development and disease. We found recently that Wnt proteins are unusual growth factors, because they are lipid-modified. We discovered that Wnt proteins promote the proliferation of stem cells of various origins. Current work is directed at understanding the function of the lipid on the Wnt,  using Wnt proteins as factors the expand stem cells and on understanding Wnt signaling during repair and regeneration after tissue injury."},{"lastName":"Sorkin","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Surgery"}],"primaryAppointment":"Postdoctoral Research fellow, Surgery","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=15174&type=small&showNoImage","displayName":"Michael Sorkin","firstName":"Michael","href":"http://med.stanford.edu/profiles/postdocs/researcher/Michael_Sorkin","researchInterest":""},{"lastName":"Zhao","clinicalFocus":[],"appointments":[{"appointment":"MD Student, School of Medicine"},{"appointment":"Ph.D., Stem Cell"}],"primaryAppointment":"MD Student, School of Medicine","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=18651&type=small&showNoImage","displayName":"Ludan \"Dani\" Zhao","firstName":"Ludan","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Ludan_Zhao","researchInterest":""},{"lastName":"Kuo","clinicalFocus":[{"focus":"Medical Oncology"}],"appointments":[{"appointment":"Professor,Medicine - Hematology"},{"appointment":"Member,Child Health Research Institute"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Member,Bio-X"},{"appointment":"Professor (By courtesy),Chemical and Systems Biology"}],"primaryAppointment":"Professor,Medicine - Hematology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=5906&type=small&showNoImage","displayName":"Calvin Kuo","firstName":"Calvin","href":"http://stanfordhospital.org/profiles/Calvin_Kuo","researchInterest":"We explore angiogenesis, cancer genomics, intestinal stem cells, and hepatic glucose metabolism.  Angiogenesis projects include endothelial miRNA and GPCR ko mice, blood-brain barrier regulation, stroke therapeutics and anti-angiogenic cancer therapy.  Intestinal stem cell projects use primary intestinal culture and mouse genetics to study injury-inducible vs homeostatic stem cells.  We use primary organoid cultures of diverse tissues for oncogene functional screening and therapeutics discovery."},{"lastName":"Dutta","clinicalFocus":[{"focus":"Pediatric Surgery"},{"focus":"Surgery, Pediatric"}],"appointments":[{"appointment":"Associate Professor - Med Center Line,Surgery - Pediatric Surgery"},{"appointment":"Associate Professor - Med Center Line,Pediatrics"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Associate Professor - Med Center Line,Surgery - Pediatric Surgery","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=6473&type=small&showNoImage","displayName":"Sanjeev Dutta, MD MA FRCSC FACS","firstName":"Sanjeev","href":"http://stanfordhospital.org/profiles/Sanjeev_Dutta","researchInterest":"Minimal Access and Scarless Surgery\r\n\r\nHirschsprung Disease\r\n\r\nEsophageal Atresia\r\n\r\nLiver and Bile Duct Surgery\r\n\r\nSurgical Management of Hereditary Spherocytosis\r\n\r\nShort Bowel Syndrome\r\n\r\nSurgical Innovation and Emerging Technologies\r\n\r\nSurgical Education and Simulation"},{"lastName":"Calos","clinicalFocus":[],"appointments":[{"appointment":"Professor,Genetics"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Genetics","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=4100&type=small&showNoImage","displayName":"Michele Calos","firstName":"Michele","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Michele_Calos","researchInterest":"My lab is developing innovative gene and cell therapies for genetic diseases, with a focus on stem cell therapies and regenerative medicine.  \r\n\r\nWe have created novel methods for inserting therapeutic genes into the chromosomes at specific places by using homologous recombination and recombinase enzymes.   \r\n\r\nWe are working on two forms of muscular dystrophy.  \r\n\r\nWe created induced pluripotent stem cells from patient fibroblasts, added therapeutic genes, differentiated, and engrafted the cells."},{"lastName":"Popat","clinicalFocus":[],"appointments":[{"appointment":"Clinical Assistant Professor,Health Research & Policy - Epidemiology"}],"primaryAppointment":"Clinical Assistant Professor,Health Research & Policy - Epidemiology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=5863&type=small&showNoImage","displayName":"Rita Popat","firstName":"Rita","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Rita_Popat","researchInterest":"My research interest focuses on the epidemiology of Parkinson\u0092s disease and amyotrophic lateral sclerosis, specifically evaluating the genetic and environmental contributions to these neurodegenerative disorders.  I am also interested in studying the relation of cognition, estradiol exposure (endogenous and exogenous), and genetic factors."},{"lastName":"Lan","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Radiology"}],"primaryAppointment":"Postdoctoral Research fellow, Radiology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=13653&type=small&showNoImage","displayName":"Feng Lan","firstName":"Feng","href":"http://med.stanford.edu/profiles/postdocs/researcher/Feng_Lan","researchInterest":""},{"lastName":"So","clinicalFocus":[{"focus":"Liver Cancer"},{"focus":"Liver Cancer - Surgery"},{"focus":"Gastrointestinal Cancers - Surgical Oncology"},{"focus":"General Surgery"}],"appointments":[{"appointment":"Professor - Med Center Line,Surgery - General Surgery"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Professor - Med Center Line,Surgery - General Surgery","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=4206&type=small&showNoImage","displayName":"Samuel So","firstName":"Samuel","href":"http://stanfordhospital.org/profiles/Samuel_So","researchInterest":"Through a 3 pronged comprehensive program: translational and clinical research, early detection and  treatment, and promoting education, awareness and immunization, we are working towards the development of new strategies that will lead to the elimination of hepatitis B worldwide and reduce the threat and incidence of liver cancer. Our current research efforts focus on evaluating potential new diagnostic and treatment markers and novel targeted therapy for primary liver cancer."},{"lastName":"Giaccia","clinicalFocus":[],"appointments":[{"appointment":"Professor,Radiation Oncology - Radiation and Cancer Biology"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Professor (By courtesy),Obstetrics & Gynecology"},{"appointment":"Professor (By courtesy),Surgery"}],"primaryAppointment":"Professor,Radiation Oncology - Radiation and Cancer Biology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=4141&type=small&showNoImage","displayName":"Amato J. Giaccia","firstName":"Amato","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Amato_Giaccia","researchInterest":"During the last five years, we have identified several small molecules that kill VHL deficient renal cancer cells through a synthetic lethal screening approach. Another major interest of my laboratory is in identifying hypoxia-induced genes involved in invasion and metastases. We are also investigating how hypoxia regulates gene expression epigenetically."},{"lastName":"Desser","clinicalFocus":[{"focus":"Diagnostic Radiology"},{"focus":"Radiology"},{"focus":"Ultrasound"}],"appointments":[{"appointment":"Associate Professor - Med Center Line,Radiology - Diagnostic Radiology"}],"primaryAppointment":"Associate Professor - Med Center Line,Radiology - Diagnostic Radiology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=4230&type=small&showNoImage","displayName":"Terry Desser","firstName":"Terry","href":"http://stanfordhospital.org/profiles/Terry_Desser","researchInterest":"Imaging of gastrointestinal tract cancer\r\nUltrasound\r\nSimulated learning environment"},{"lastName":"Rodgers","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Neurology & Neurological Sciences"}],"primaryAppointment":"Postdoctoral Research fellow, Neurology & Neurological Sciences","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=19007&type=small&showNoImage","displayName":"Joseph T. Rodgers","firstName":"Joseph","href":"http://med.stanford.edu/profiles/postdocs/researcher/Joseph_Rodgers","researchInterest":""},{"lastName":"Felsher","clinicalFocus":[{"focus":"Hodgkin's Disease"},{"focus":"Hodgkin's Disease - Hematology"},{"focus":"Hodgkin's Disease - Medical Oncology"},{"focus":"Lymphoma "},{"focus":"Oncology (Cancer)"},{"focus":"Medical Oncology"}],"appointments":[{"appointment":"Professor,Medicine - Oncology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Professor,Pathology"}],"primaryAppointment":"Professor,Medicine - Oncology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=5931&type=small&showNoImage","displayName":"Dean W. Felsher","firstName":"Dean","href":"http://stanfordhospital.org/profiles/Dean_Felsher","researchInterest":"My laboratory investigates how oncogenes initiate and sustain tumorigenesis. I have developed model systems whereby I can conditionally activate oncogenes in normal human and mouse cells in tissue culture or in specific tissues of transgenic mice. In particular using the tetracycline regulatory system, I have generated a conditional model system for MYC-induced tumors. I have shown that cancers caused by the conditional over-expression of the MYC proto-oncogene regress with its inactivation."},{"lastName":"Schaefer","clinicalFocus":[],"appointments":[{"appointment":"Visiting Assistant Professor,Neurosurgery"}],"primaryAppointment":"Visiting Assistant Professor,Neurosurgery","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=23991&type=small&showNoImage","displayName":"Richard Schaefer","firstName":"Richard","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Richard_Schaefer","researchInterest":"- derivation of neural progenitor cells from hESCs\r\n- derivation of patient specific iPSCs\r\n- mesenchymal stromal cells\r\n- immunomodulation"},{"lastName":"Connolly","clinicalFocus":[{"focus":"Anatomic Pathology"}],"appointments":[{"appointment":"Associate Professor - Med Center Line,Pathology"}],"primaryAppointment":"Associate Professor - Med Center Line,Pathology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=6324&type=small&showNoImage","displayName":"Andrew J. Connolly","firstName":"Andrew","href":"http://stanfordhospital.org/profiles/Andrew_Connolly","researchInterest":"My research interests are vascular biology and cardiovascular pathology.  We are currently working on gene expression in endothelial cells at sites of pathology."},{"lastName":"Miller","clinicalFocus":[{"focus":"Neonatal-Perinatal Medicine"},{"focus":"Neonatology"}],"appointments":[{"appointment":"Clinical Instructor,Pediatrics - Neonatal and Developmental Medicine"}],"primaryAppointment":"Clinical Instructor,Pediatrics - Neonatal and Developmental Medicine","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=11655&type=small&showNoImage","displayName":"Stephanie Miller","firstName":"Stephanie","href":"http://stanfordhospital.org/profiles/Stephanie_Miller","researchInterest":""},{"lastName":"Lau","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Surgery"}],"primaryAppointment":"Postdoctoral Research fellow, Surgery","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=30657&type=small&showNoImage","displayName":"Audrey Lau","firstName":"Audrey","href":"http://med.stanford.edu/profiles/postdocs/researcher/Audrey_Lau","researchInterest":""},{"lastName":"Pan","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Genetics"}],"primaryAppointment":"Postdoctoral Research fellow, Genetics","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=20307&type=small&showNoImage","displayName":"Cuiping Pan","firstName":"Cuiping","href":"http://med.stanford.edu/profiles/postdocs/researcher/Cuiping_Pan","researchInterest":""},{"lastName":"Hintz","clinicalFocus":[{"focus":"Neonatal-Perinatal Medicine"},{"focus":"Neonatology"}],"appointments":[{"appointment":"Professor - Med Center Line,Pediatrics - Neonatal and Developmental Medicine"},{"appointment":"Professor - Med Center Line (By courtesy),Obstetrics & Gynecology"}],"primaryAppointment":"Professor - Med Center Line,Pediatrics - Neonatal and Developmental Medicine","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=4710&type=small&showNoImage","displayName":"Susan R. Hintz, M.D., M.S. Epi.","firstName":"Susan","href":"http://stanfordhospital.org/profiles/Susan_Hintz","researchInterest":"1) Early childhood neurodevelopmental outcomes, mortality and morbidities of ELBW, extremely premature, and high-risk infants; predictive clinical factors, evidence-based interventions \r\n2) Use of advanced neuroimaging techniques in the premature and term infant; diagnostic findings, and predictors of neurodevelopmental outcomes\r\n3) Advanced therapeutic modalities: HFOV, iNO, ECMO - implementation, indications, outcomes\r\n4) Natural history and outcomes of complex fetal anomalies"},{"lastName":"Gurtner","clinicalFocus":[{"focus":"Plastic Surgery"},{"focus":"Plastic & Recon Surgery"}],"appointments":[{"appointment":"Professor - Med Center Line,Surgery - Plastic & Reconstructive Surgery"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Professor - Med Center Line (By courtesy),Materials Science and Engineering - Engineering Materials Science"}],"primaryAppointment":"Professor - Med Center Line,Surgery - Plastic & Reconstructive Surgery","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=6890&type=small&showNoImage","displayName":"Geoffrey Gurtner","firstName":"Geoffrey","href":"http://stanfordhospital.org/profiles/Geoffrey_Gurtner","researchInterest":"Geoffrey Gurtner's Lab is interested in understanding the mecahnism of new blood vessel growth following injury and how pathways of tissue regeneration and fibrosis interact in wound healing."}]}