{"result":[{"lastName":"MacIver","clinicalFocus":[],"appointments":[{"appointment":"Professor (Research),Anesthesia"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor (Research),Anesthesia","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=4009&type=small&showNoImage","displayName":"M Bruce MacIver","firstName":"M","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/M_MacIver","researchInterest":"We study drug effects on the nervous system. Cellular, synaptic and molecular drug actions are investigated using electrophysiological and pharmacological tools in cortical/hippocampal brain slice preparations. We are also interested in mechanisms of neuronal integration and synchronization, especially related to patterns of EEG activity seen in vivo and in brain slices."},{"lastName":"Hestrin","clinicalFocus":[],"appointments":[{"appointment":"Professor,Comparative Medicine"}],"primaryAppointment":"Professor,Comparative Medicine","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=4343&type=small&showNoImage","displayName":"Shaul Hestrin","firstName":"Shaul","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Shaul_Hestrin","researchInterest":"The main interest of my lab is to understand how the properties of neocortical neurons and the circuits they form give rise to cortical activity and function. Our approach includes recordings from multiple cells, calcium imaging, two-photon imaging and viral-based optogenetic methods to activate  cortical neurons as well as cortical afferents."},{"lastName":"Madison","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Molecular & Cellular Physiology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Associate Professor,Molecular & Cellular Physiology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=4321&type=small&showNoImage","displayName":"Daniel V. Madison","firstName":"Vernon","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Vernon_Madison","researchInterest":"Our laboratory uses electrophysiological techniques to study the mechanisms of synaptic transmission and plasticity in the mammalian hippocampus. One of the main focuses in the lab is in the study of synaptic long-term potentiation (LTP). LTP is the persistent increase in synaptic strength that occurs after a period of heavy activity in a synaptic connection. It is the most widely studied and compelling model for mechanisms underlying memory formation in the mammalian central nervous system."},{"lastName":"Garner","clinicalFocus":[],"appointments":[{"appointment":"Professor,Psychiatry & Behavioral Science - Psychiatry/Neuroscience/MSLS"},{"appointment":"Member,Bio-X"},{"appointment":"Professor (By courtesy),Neurology & Neurological Sciences"}],"primaryAppointment":"Professor,Psychiatry & Behavioral Science - Psychiatry/Neuroscience/MSLS","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=3890&type=small&showNoImage","displayName":"Craig C. Garner","firstName":"Craig","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Craig_Garner","researchInterest":"Our laboratory is studying synapse formation, stability and elimination at a variety of levels, e.g. from molecules to behavior.  A primary focus of the lab is to understanding the role that individual molecules play in the assembly and function of synaptic junctions.  In addition we evaluating a variety of potential treatments for cognitive impairment in Down syndrome in part by assessing the impact specific drugs on cognitive function in mouse models of Down syndrome."},{"lastName":"Angelotti","clinicalFocus":[{"focus":"Anesthesia"},{"focus":"Critical Care"}],"appointments":[{"appointment":"Associate Professor - Med Center Line,Anesthesia"}],"primaryAppointment":"Associate Professor - Med Center Line,Anesthesia","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=4339&type=small&showNoImage","displayName":"Timothy Angelotti MD, PhD","firstName":"Timothy","href":"http://stanfordhospital.org/profiles/Timothy_Angelotti","researchInterest":"My research efforts are focused on investigating the pharmacological and physiological interface of the autonomic nervous system with effector organs. Utilizing molecular, cellular, and electrophysiological techniques, we are examining alpha2 adrenergic receptor function in cultured sympathetic neurons. Future research aims will be directed toward understanding neurotransmitter release in general."},{"lastName":"Lee","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Bioengineering"}],"primaryAppointment":"Postdoctoral Research fellow, Bioengineering","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=23467&type=small&showNoImage","displayName":"Soo Yeun Lee","firstName":"Soo Yeun","href":"http://med.stanford.edu/profiles/postdocs/researcher/Soo Yeun_Lee","researchInterest":""},{"lastName":"Bertaccini","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor - Med Center Line,Anesthesia"},{"appointment":"Professor - Med Center Line,Anesthesia"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Associate Professor - Med Center Line,Anesthesia","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=4079&type=small&showNoImage","displayName":"Edward Bertaccini","firstName":"Edward","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Edward_Bertaccini","researchInterest":"molecular modeling of anesthetic-protein interactions, molecular modeling of the ligand-gated ion channels"},{"lastName":"Panousis","clinicalFocus":[{"focus":"Anesthesia"}],"appointments":[{"appointment":"Clinical Assistant Professor,Anesthesia"}],"primaryAppointment":"Clinical Assistant Professor,Anesthesia","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=12473&type=small&showNoImage","displayName":"Periklis Panousis","firstName":"Periklis","href":"http://stanfordhospital.org/profiles/Periklis_Panousis","researchInterest":""},{"lastName":"Carroll","clinicalFocus":[{"focus":"Pain Management"},{"focus":"Neuropathic Pain"},{"focus":"Anesthesia"}],"appointments":[{"appointment":"Assistant Professor - Med Center Line,Anesthesia"}],"primaryAppointment":"Assistant Professor - Med Center Line,Anesthesia","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=6177&type=small&showNoImage","displayName":"Ian Carroll, MD, MS","firstName":"Ian","href":"http://stanfordhospital.org/profiles/Ian_Carroll","researchInterest":"Factors causing prolonged post-surgical pain and prolonged opioid use."},{"lastName":"Doufas","clinicalFocus":[{"focus":"Anesthesia"},{"focus":"Neurosurgical Anesthesia"}],"appointments":[{"appointment":"Associate Professor - Med Center Line,Anesthesia"}],"primaryAppointment":"Associate Professor - Med Center Line,Anesthesia","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=7905&type=small&showNoImage","displayName":"Anthony G. Doufas, M.D., Ph.D.","firstName":"Anthony","href":"http://stanfordhospital.org/profiles/Anthony_Doufas","researchInterest":"My research focuses on the relationship between sleep abnormalities and pain behavior and opioid pharmacology in the postoperative, as well as chronic pain setting. More  specifically, I am interested in delineating the effect of the different components of sleep-diosordered breathing, like nocturnal recurrent hypoxemia and sleep fragmentation on pain behavior in the acute and/or chronic care setting."},{"lastName":"Saidman","clinicalFocus":[],"appointments":[{"appointment":"Emeritus Faculty-Med Ctr Line,Anesthesia"}],"primaryAppointment":"Emeritus Faculty-Med Ctr Line,Anesthesia","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=4442&type=small&showNoImage","displayName":"Lawrence Saidman","firstName":"Lawrence","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Lawrence_Saidman","researchInterest":""},{"lastName":"Trudell","clinicalFocus":[],"appointments":[{"appointment":"Professor,Anesthesia"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Anesthesia","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=4617&type=small&showNoImage","displayName":"James Trudell","firstName":"James","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/James_Trudell","researchInterest":"Molecular theories of anesthesia. My emphasis is on the molecular interactions of inhalational anesthetics and alcohol. I perform computational chemistry simulations on how these molecules bind to putative receptor sites. I am also interested in modeling receptor proteins in which chimeras cause loss or enhancement of anesthetic sensitivity."},{"lastName":"Lammel","clinicalFocus":[],"appointments":[{"appointment":"Basic Life Science Research Associate,Psychiatry & Behavioral Science - Psychiatry/Neuroscience/MSLS"}],"primaryAppointment":"Basic Life Science Research Associate,Psychiatry & Behavioral Science - Psychiatry/Neuroscience/MSLS","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=10914&type=small&showNoImage","displayName":"Stephan Lammel","firstName":"Stephan","href":"http://stanfordhospital.org/profiles/Stephan_Lammel","researchInterest":""},{"lastName":"Giocomo","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Neurobiology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Assistant Professor,Neurobiology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=35065&type=small&showNoImage","displayName":"Lisa Giocomo","firstName":"Lisa","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Lisa_Giocomo","researchInterest":"My laboratory studies the cellular and molecular mechanisms underlying the organization of cortical circuits important for spatial navigation and memory. We are particularly focused on medial entorhinal cortex, where many neurons fire in spatially specific patterns and thus offer a measurable output for molecular manipulations. We combine electrophysiology, genetic approaches and behavioral paradigms to unravel the mechanisms and behavioral relevance of non-sensory cortical organization. Our fi"},{"lastName":"Ruiz-Lozano","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor (Research),Pediatrics - Cardiology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Child Health Research Institute"}],"primaryAppointment":"Associate Professor (Research),Pediatrics - Cardiology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=18359&type=small&showNoImage","displayName":"Pilar Ruiz-Lozano, Ph.D.","firstName":"Pilar","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Pilar_Ruiz-Lozano","researchInterest":"Cardiac development and repair"},{"lastName":"Clusin","clinicalFocus":[{"focus":"Cardiovascular Disease"},{"focus":"Cardiovascular Medicine"},{"focus":"Electrocardiography"}],"appointments":[{"appointment":"Associate Professor,Medicine - Cardiovascular Medicine"}],"primaryAppointment":"Associate Professor,Medicine - Cardiovascular Medicine","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=4502&type=small&showNoImage","displayName":"William Clusin, MD","firstName":"William","href":"http://stanfordhospital.org/profiles/William_Clusin","researchInterest":"Cardiac action potentials; tissue culture, voltage, clamp technique; role of calcium in ischemia arrhythmias; coronary, artery disease; myocardial infarction."},{"lastName":"Meyer","clinicalFocus":[],"appointments":[{"appointment":"Professor,Chemical and Systems Biology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Chemical and Systems Biology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=4007&type=small&showNoImage","displayName":"Tobias Meyer","firstName":"Tobias","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Tobias_Meyer","researchInterest":"CELLULAR INFORMATION PROCESSING  The main problem in signal transduction is to understand how different receptor-stimuli specifically control diverse cell functions. We are using automated microscopy, live-cell fluorescent biosensors and perturbations of predicted signaling proteins to systematically dissect signaling networks.  This allows us to identify signaling modules and to elucidate and ultimately model the flow of cellular information."},{"lastName":"Fijalkowski","clinicalFocus":[],"appointments":[{"appointment":"MD Student, School of Medicine"},{"appointment":"MS, Dean's Office"},{"appointment":"Temp - Non-Exempt,Ophthalmology"}],"primaryAppointment":"MD Student, School of Medicine","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=17803&type=small&showNoImage","displayName":"Natalia Fijalkowski","firstName":"Natalia","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Natalia_Fijalkowski","researchInterest":""},{"lastName":"Tan","clinicalFocus":[{"focus":"Kidney and Pancreas Transplantation"},{"focus":"Nephrology"},{"focus":"Nephrology (Kidney)"}],"appointments":[{"appointment":"Associate Professor - Med Center Line,Medicine - Nephrology"},{"appointment":"MS, Dean's Office"}],"primaryAppointment":"Associate Professor - Med Center Line,Medicine - Nephrology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=3846&type=small&showNoImage","displayName":"Jane C. Tan","firstName":"Jane","href":"http://stanfordhospital.org/profiles/Jane_Tan","researchInterest":"My research relates to issues pertaining to clinical kidney transplantation. We have ongoing studies on the following topics.\r\n1. Renal senescence and kidney transplant, and chronic allograft nephropathy.\r\n2. Living donor safety and response to uninephrectomy.\r\n3. Biomarkers for post-transplant monitoring."},{"lastName":"Dash","clinicalFocus":[{"focus":"Cardiovascular Disease"},{"focus":"Cardiovascular Medicine"}],"appointments":[{"appointment":"Assistant Professor - Med Center Line,Medicine - Cardiovascular Medicine"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Assistant Professor - Med Center Line,Medicine - Cardiovascular Medicine","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=8685&type=small&showNoImage","displayName":"Rajesh Dash, MD, PhD","firstName":"Rajesh","href":"http://stanfordhospital.org/profiles/Rajesh_Dash","researchInterest":"My research focuses on imaging cell signaling in the heart.  I am developing molecular imaging probes that  track to injured heart tissue, such that non-invasive imaging techniques, like cardiac MRI, can visualize these probe signals in real-time.  The translational goal of my research is to develop new ways to detect early cardiac injury before permanent damage occurs, so that preventive medical therapy can be started."},{"lastName":"Malenka","clinicalFocus":[],"appointments":[{"appointment":"Professor,Psychiatry & Behavioral Science - Psychiatry/Neuroscience/MSLS"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Psychiatry & Behavioral Science - Psychiatry/Neuroscience/MSLS","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=4670&type=small&showNoImage","displayName":"Robert Malenka","firstName":"Robert","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Robert_Malenka","researchInterest":"Long-lasting changes in synaptic strength are important for the modification of neural circuits by experience. A major goal of my laboratory is to elucidate the molecular events that trigger various forms of synaptic plasticity and the modifications in synaptic proteins that are responsible for the changes in synaptic efficacy."}]}