{"result":[{"lastName":"Nguyen","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Medicine"}],"primaryAppointment":"Postdoctoral Research fellow, Medicine","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=32954&type=small&showNoImage","displayName":"Tom Nguyen","firstName":"Tom","href":"http://med.stanford.edu/profiles/postdocs/researcher/Tom_Nguyen","researchInterest":""},{"lastName":"Smith","clinicalFocus":[],"appointments":[{"appointment":"Emeritus Faculty, Acad Council,Neurology & Neurological Sciences"}],"primaryAppointment":"Emeritus Faculty, Acad Council,Neurology & Neurological Sciences","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=7015&type=small&showNoImage","displayName":"Marion Smith","firstName":"Marion","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Marion_Smith","researchInterest":""},{"lastName":"Steinman","clinicalFocus":[{"focus":"Neurology"},{"focus":"Neurology, Pediatric"},{"focus":"Multiple Sclerosis, Myasthenia Gravis, Immune Disorders"}],"appointments":[{"appointment":"Professor,Neurology & Neurological Sciences"},{"appointment":"Member,Bio-X"},{"appointment":"Professor,Pediatrics"}],"primaryAppointment":"Professor,Neurology & Neurological Sciences","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=3784&type=small&showNoImage","displayName":"Lawrence Steinman","firstName":"Lawrence","href":"http://stanfordhospital.org/profiles/Lawrence_Steinman","researchInterest":"Our laboratory is dedicated to understanding the pathogenesis of autoimmune diseases, particularly multiple sclerosis. We have developed several new therapies for autoimmunity, including some in Phase 2 clinical trials, as well as one approved drug, natalizumab. We have developed microarray technology for detecting autoantibodies to myelin proteins and lipids. We employ a diverse range of molecular and celluar approaches to trying to understand multiple sclerosis."},{"lastName":"Sobel","clinicalFocus":[],"appointments":[{"appointment":"Professor,Pathology"},{"appointment":"Professor (By courtesy),Neurology & Neurological Sciences"}],"primaryAppointment":"Professor,Pathology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=4269&type=small&showNoImage","displayName":"Raymond A. Sobel, M.D.","firstName":"Raymond","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Raymond_Sobel","researchInterest":"We study cellular and molecular mechanisms of immune-mediated injury in central nervous system (CNS) tissues that are altered in multiple sclerosis (MS). Tissues of patients and of animals with experimental allergic encephalomyelitis are analyzed using histology and immunohistochemistry. We currently are studying the cross-recognition of neurons by antibodies against myelin proteolipid protein epitopes. Similar cross-recognition may link anti-myelin immunity with neurodegeneration in MS."},{"lastName":"Barres","clinicalFocus":[],"appointments":[{"appointment":"Professor,Neurobiology"},{"appointment":"Member,Bio-X"},{"appointment":"Professor,Developmental Biology"},{"appointment":"Professor,Neurology & Neurological Sciences"}],"primaryAppointment":"Professor,Neurobiology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=4239&type=small&showNoImage","displayName":"Ben Barres","firstName":"Ben","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Ben_Barres","researchInterest":"Our lab is interested in the neuronal-glial interactions that underlie the development and function of the mammlian central nervous system."},{"lastName":"Robinson","clinicalFocus":[{"focus":"Immunology and Rheumatology"},{"focus":"Rheumatology"}],"appointments":[{"appointment":"Associate Professor,Medicine - Immunology & Rheumatology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Associate Professor,Medicine - Immunology & Rheumatology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=4730&type=small&showNoImage","displayName":"William Robinson","firstName":"William","href":"http://stanfordhospital.org/profiles/William_Robinson","researchInterest":"Our lab studies the molecular mechanisms of and develops therapies to treat autoimmune and rheumatic diseases, with a focus on rheumatoid arthritis, multiple sclerosis, and osteoarthritis. \r\n\r\nThe overriding objectives of our laboratory are:\r\n\r\n1. To investigate the mechanisms underlying autoimmune diseases.\r\n\r\n2. To develop diagnostics and therapeutics for autoimmune diseases.\r\n\r\n3. To investigate the role of inflammation in osteoarthritis."},{"lastName":"Kurnellas","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Neurology & Neurological Sciences"}],"primaryAppointment":"Postdoctoral Research fellow, Neurology & Neurological Sciences","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=14640&type=small&showNoImage","displayName":"Michael Kurnellas","firstName":"Michael","href":"http://med.stanford.edu/profiles/postdocs/researcher/Michael_Kurnellas","researchInterest":""},{"lastName":"Giffard","clinicalFocus":[],"appointments":[{"appointment":"Professor,Anesthesia"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Anesthesia","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=4657&type=small&showNoImage","displayName":"Rona Giffard","firstName":"Rona","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Rona_Giffard","researchInterest":"Astrocytes, microglia and neurons interact, and have unique vulnerabilities to injury based on their patterns of gene expression and their functional roles. We focus on the cellular and molecular basis for brain cell injury in stroke. We study gene therapy with heat shock and other protective proteins, the effects of specific microRNAs, changes in mitochondrial function, oxidative stress and inflammation during ischemia. We also model cell death pathways and the effects of Hsp70."},{"lastName":"Reimer","clinicalFocus":[{"focus":"Neurology"}],"appointments":[{"appointment":"Associate Professor - Med Center Line,Neurology & Neurological Sciences"},{"appointment":"Member,Bio-X"},{"appointment":"Associate Professor - Med Center Line (By courtesy),Molecular & Cellular Physiology"}],"primaryAppointment":"Associate Professor - Med Center Line,Neurology & Neurological Sciences","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=3819&type=small&showNoImage","displayName":"Richard J. Reimer, MD","firstName":"Richard","href":"http://stanfordhospital.org/profiles/Richard_Reimer","researchInterest":"Reimer Lab interests\r\n\r\nA primary interest of our lab is to understand how nerve cells make and recycle neurotransmitters, the small molecules that they use to communicate with each other. In better defining these processes we hope to achieve our long-term goal of identifying novel sites for treatment of diseases such as epilepsy and Parkinson Disease. In our studies on neurotransmitter metabolism we have focused our efforts on transporters, a functional class of proteins that move neurotransmi"},{"lastName":"Vogel","clinicalFocus":[{"focus":"Pathology"}],"appointments":[{"appointment":"Professor - Med Center Line,Pathology"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Professor - Med Center Line,Pediatrics"},{"appointment":"Professor - Med Center Line (By courtesy),Neurosurgery"},{"appointment":"Professor - Med Center Line (By courtesy),Neurology & Neurological Sciences"},{"appointment":"Professor - Med Center Line (By courtesy),Comparative Medicine"}],"primaryAppointment":"Professor - Med Center Line,Pathology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=3892&type=small&showNoImage","displayName":"Hannes Vogel","firstName":"Hannes","href":"http://stanfordhospital.org/profiles/Hannes_Vogel","researchInterest":"My research interests include nerve and muscle pathology, mitochondrial diseases, pediatric neurooncology, and transgenic mouse pathology."},{"lastName":"Ajami","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Neurology & Neurological Sciences"}],"primaryAppointment":"Postdoctoral Research fellow, Neurology & Neurological Sciences","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=30648&type=small&showNoImage","displayName":"Bahareh Ajami","firstName":"Bahareh","href":"http://med.stanford.edu/profiles/postdocs/researcher/Bahareh_Ajami","researchInterest":""},{"lastName":"Utz","clinicalFocus":[{"focus":"Immunology and Rheumatology"},{"focus":"Rheumatology"}],"appointments":[{"appointment":"Professor,Medicine - Immunology & Rheumatology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Medicine - Immunology & Rheumatology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=4001&type=small&showNoImage","displayName":"Paul Utz","firstName":"Paul","href":"http://stanfordhospital.org/profiles/Paul_Utz","researchInterest":"The long-term research goal of Dr. Utz\u0092s laboratory is (1) to develop a better understanding of the pathogenic mechanisms underlying systemic lupus erythematosus (SLE) and other autoimmune diseases by exploring signaling pathways that are activated during apoptosis; and (2) to better understand the complicated process of programmed cell death."},{"lastName":"Lane","clinicalFocus":[],"appointments":[{"appointment":"Emeritus Faculty-Med Ctr Line,Radiology"}],"primaryAppointment":"Emeritus Faculty-Med Ctr Line,Radiology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=4172&type=small&showNoImage","displayName":"Barton Lane","firstName":"Barton","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Barton_Lane","researchInterest":"As a professor in the Medical Center Line, my primary investigative interest has been in clinical neuroradiology. This encompasses spinal cord and spine disease, degenerative and demyelinating diseases of the central nervous system, strokes and infarction, and chronic epilepsy syndromes. Facial and head and neck vascular malformations and hemangiomas have been a focus of interest for many years, with collaborative projects involving dermatology and functional restoration services."},{"lastName":"Dunn","clinicalFocus":[{"focus":"Multiple Sclerosis"},{"focus":"Neuromyelitis Optica"},{"focus":"Transverse Myelitis"},{"focus":"Neurology"}],"appointments":[{"appointment":"Clinical Professor,Neurology & Neurological Sciences"}],"primaryAppointment":"Clinical Professor,Neurology & Neurological Sciences","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=8456&type=small&showNoImage","displayName":"Jeffrey Dunn, MD","firstName":"Jeffrey","href":"http://stanfordhospital.org/profiles/Jeffrey_Dunn","researchInterest":"Translational research in the human application of emerging immunotherapies for neurological disease, focusing on Multiple Sclerosis, CIS, transverse myelitis and Neuromyelitis Optica (NMO). Collaborative research with Stanford and extramural scientific faculty to identify biomarkers of disease activity and treatment response in humans. Clinical trials to assess efficacy of emerging treatments for MS, CIS and NMO, recently including trials of alemtuzumab, oral sphingosine 1 phosphate inhibition"},{"lastName":"Ronaghi","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Otolaryngology (Head and Neck Surgery)"}],"primaryAppointment":"Postdoctoral Research fellow, Otolaryngology (Head and Neck Surgery)","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=18186&type=small&showNoImage","displayName":"Mohammad Ronaghi","firstName":"Mohammad","href":"http://med.stanford.edu/profiles/postdocs/researcher/Mohammad_Ronaghi","researchInterest":""},{"lastName":"Buckwalter","clinicalFocus":[{"focus":"Neurology"},{"focus":"Neurologic Critical Care"}],"appointments":[{"appointment":"Assistant Professor - Med Center Line,Neurology & Neurological Sciences"},{"appointment":"Member,Neurology & Neurological Sciences"},{"appointment":"Assistant Professor - Med Center Line,Neurosurgery"}],"primaryAppointment":"Assistant Professor - Med Center Line,Neurology & Neurological Sciences","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=6463&type=small&showNoImage","displayName":"Marion S. Buckwalter","firstName":"Marion","href":"http://stanfordhospital.org/profiles/Marion_Buckwalter","researchInterest":"The goal of the Buckwalter Lab is to improve how people recover after a stroke. We use basic research to understand the cells, proteins, and genes that lead to successful recovery of function, and also how complications develop that impact quality of life after stroke. Ongoing projects are focused on understanding how inflammatory responses are regulated after a stroke and how to make recovery faster and better after stroke."},{"lastName":"Dodd","clinicalFocus":[{"focus":"Neurosurgery"}],"appointments":[{"appointment":"Assistant Professor - Med Center Line,Neurosurgery"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Assistant Professor - Med Center Line,Radiology"}],"primaryAppointment":"Assistant Professor - Med Center Line,Neurosurgery","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=6790&type=small&showNoImage","displayName":"Robert Dodd","firstName":"Robert","href":"http://stanfordhospital.org/profiles/Robert_Dodd","researchInterest":"Dr. Dodd is involved in clinical trials using endovascular coils that have a fiber coating that help heal aneurysms of the neck and can prevent an aneurysm from reforming. He uses minimally invasive endoscopic techniques to treat brain tumors.\r\n\r\nDodd's research interests are in cerebral blood vessel reactivity and stroke."},{"lastName":"Levesque","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Radiology"}],"primaryAppointment":"Postdoctoral Research fellow, Radiology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=16504&type=small&showNoImage","displayName":"Ives Levesque","firstName":"Ives","href":"http://med.stanford.edu/profiles/postdocs/researcher/Ives_Levesque","researchInterest":""},{"lastName":"Wyss-Coray","clinicalFocus":[],"appointments":[{"appointment":"Professor,Neurology & Neurological Sciences"},{"appointment":"Member,Child Health Research Institute"}],"primaryAppointment":"Professor,Neurology & Neurological Sciences","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=3929&type=small&showNoImage","displayName":"Tony Wyss-Coray","firstName":"Tony","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Tony_Wyss-Coray","researchInterest":"Use of genetic and molecular tools to dissect immune and inflammatory pathways in Alzheimer's and neurodegeneration."},{"lastName":"Nelson","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Health Research & Policy - Epidemiology"}],"primaryAppointment":"Associate Professor,Health Research & Policy - Epidemiology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=4277&type=small&showNoImage","displayName":"Lorene Nelson, PhD","firstName":"Lorene","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Lorene_Nelson","researchInterest":"Primary research interests: (1) genetic and environmental determinants of neurodegenerative disorders, including Parkinson's disease, amyotrophic lateral sclerosis and multiple sclerosis, (2) genetic epidemiology and approaches for identifying gene-environment interactions, (3) genetic and environmental determinants of autoimmune disease."},{"lastName":"Lin","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Pediatrics - Human Gene Therapy"},{"appointment":"Assistant Professor,Bioengineering"},{"appointment":"Member,Child Health Research Institute"}],"primaryAppointment":"Assistant Professor,Pediatrics - Human Gene Therapy","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=13015&type=small&showNoImage","displayName":"Michael Lin","firstName":"Michael","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Michael_Lin","researchInterest":"Our lab applies biochemical and engineering principles to the development of protein-based tools for molecular imaging and gene therapy. Topics of investigation include fluorescent proteins structure and biophysics, fluorescent protein-based biosensors, spatiotemporal analysis of protein translation pathways, chemical control of protein translation, and light-responsive proteins."}]}