{"result":[{"lastName":"Chen","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Psychiatry & Behavioral Science - Center for Interdisciplinary Brain Sciences Research"}],"primaryAppointment":"Associate Professor,Psychiatry & Behavioral Science - Center for Interdisciplinary Brain Sciences Research","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=20934&type=small&showNoImage","displayName":"Lu Chen","firstName":"Lu","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Lu_Chen","researchInterest":"What distinguishes us humans from other animals is our ability to undergo complex behavior. The synapses are the structural connection between neurons that mediates the communication between neurons, which underlies our various cognitive function. My research program aims to understand the cellular and molecular mechanisms that underlie synapse function during behavior in the developing and mature brain, and how synapse function is altered during mental retardation."},{"lastName":"Kendig","clinicalFocus":[],"appointments":[{"appointment":"Emeritus Faculty, Acad Council,Anesthesia"}],"primaryAppointment":"Emeritus Faculty, Acad Council,Anesthesia","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=4161&type=small&showNoImage","displayName":"Joan Kendig","firstName":"Joan","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Joan_Kendig","researchInterest":"My laboratory tries to find out how pharmacologic agents used in the practice of anesthesia (general anesthetic and analgesic agents) lead to therapeutically desireable endpoints including unconsciousness, immobility and absence of pain. The old idea that general anesthetics are uniformly non-specific \"membrane stabilizers\" is giving way to a new realization that these agents exert specific actions on particular ion channels and intracellular signalling systems."},{"lastName":"Hestrin","clinicalFocus":[],"appointments":[{"appointment":"Professor,Comparative Medicine"}],"primaryAppointment":"Professor,Comparative Medicine","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=4343&type=small&showNoImage","displayName":"Shaul Hestrin","firstName":"Shaul","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Shaul_Hestrin","researchInterest":"The main interest of my lab is to understand how the properties of neocortical neurons and the circuits they form give rise to cortical activity and function. Our approach includes recordings from multiple cells, calcium imaging, two-photon imaging and viral-based optogenetic methods to activate  cortical neurons as well as cortical afferents."},{"lastName":"Malenka","clinicalFocus":[],"appointments":[{"appointment":"Professor,Psychiatry & Behavioral Science - Psychiatry/Neuroscience/MSLS"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Psychiatry & Behavioral Science - Psychiatry/Neuroscience/MSLS","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=4670&type=small&showNoImage","displayName":"Robert Malenka","firstName":"Robert","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Robert_Malenka","researchInterest":"Long-lasting changes in synaptic strength are important for the modification of neural circuits by experience. A major goal of my laboratory is to elucidate the molecular events that trigger various forms of synaptic plasticity and the modifications in synaptic proteins that are responsible for the changes in synaptic efficacy."},{"lastName":"Chen","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Neurosciences Institute"}],"primaryAppointment":"Postdoctoral Research fellow, Neurosciences Institute","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=20866&type=small&showNoImage","displayName":"Lulu Chen","firstName":"Lulu","href":"http://med.stanford.edu/profiles/postdocs/researcher/Lulu_Chen","researchInterest":""},{"lastName":"McConnell","clinicalFocus":[],"appointments":[{"appointment":"Professor,Biology (School of Humanities and Sciences)"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Biology (School of Humanities and Sciences)","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=5928&type=small&showNoImage","displayName":"Susan K. McConnell","firstName":"Susan","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Susan_McConnell","researchInterest":"The McConnell Lab studies the cellular and molecular mechanisms that underlie the development of the mammalian cerebral cortex.  Our work focuses on the earliest events that pattern the developing forebrain, enable neural progenitors to divide asymmetrically to generate young neurons, propel the migration of postmitotic neurons outward into their final positions, and sculpt the fates and phenotypes of the neurons as they differentiate."},{"lastName":"MacIver","clinicalFocus":[],"appointments":[{"appointment":"Professor (Research),Anesthesia"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor (Research),Anesthesia","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=4009&type=small&showNoImage","displayName":"M Bruce MacIver","firstName":"M","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/M_MacIver","researchInterest":"We study drug effects on the nervous system. Cellular, synaptic and molecular drug actions are investigated using electrophysiological and pharmacological tools in cortical/hippocampal brain slice preparations. We are also interested in mechanisms of neuronal integration and synchronization, especially related to patterns of EEG activity seen in vivo and in brain slices."},{"lastName":"Murphy","clinicalFocus":[{"focus":"Psychiatry"},{"focus":"Geriatric Psychiatry"},{"focus":"Neuropsychiatry"},{"focus":"Dementia"},{"focus":"Mood Disorders"}],"appointments":[{"appointment":"Professor,Psychiatry & Behavioral Science - Psychiatry/Neuroscience/MSLS"}],"primaryAppointment":"Professor,Psychiatry & Behavioral Science - Psychiatry/Neuroscience/MSLS","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=4515&type=small&showNoImage","displayName":"Greer Murphy M.D., Ph.D.","firstName":"Greer","href":"http://stanfordhospital.org/profiles/Greer_Murphy","researchInterest":"Pharmacogenetics of mood disorders and nicotine addiction.  Glial cell neurotoxicity and neuroprotection in Alzheimer's disease. Genome wide expression analysis of mouse models for Alzheimer's disease."},{"lastName":"Leone-Haditsch","clinicalFocus":[],"appointments":[{"appointment":"Instructor,Neurosurgery"}],"primaryAppointment":"Instructor,Neurosurgery","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=23617&type=small&showNoImage","displayName":"Ursula Haditsch","firstName":"Ursula","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Ursula_Leone-Haditsch","researchInterest":""},{"lastName":"Zeineh","clinicalFocus":[{"focus":"Diagnostic Radiology"}],"appointments":[{"appointment":"Assistant Professor - Med Center Line,Radiology - Diagnostic Radiology"}],"primaryAppointment":"Assistant Professor - Med Center Line,Radiology - Diagnostic Radiology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=16920&type=small&showNoImage","displayName":"Michael Zeineh","firstName":"Michael","href":"http://stanfordhospital.org/profiles/Michael_Zeineh","researchInterest":""},{"lastName":"Li","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Molecular & Cellular Physiology"}],"primaryAppointment":"Postdoctoral Research fellow, Molecular & Cellular Physiology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=35683&type=small&showNoImage","displayName":"Dong Li","firstName":"Dong","href":"http://med.stanford.edu/profiles/postdocs/researcher/Dong_Li","researchInterest":""},{"lastName":"Wagner","clinicalFocus":[],"appointments":[{"appointment":"Member,Bio-X"}],"primaryAppointment":"Member,Bio-X","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=8084&type=small&showNoImage","displayName":"Anthony Wagner","firstName":"Anthony","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Anthony_Wagner","researchInterest":"Cognitive neuroscience of memory and cognitive/executive control in young and older adults. Research interests include encoding and retrieval mechanisms; interactions between declarative, nondeclarative, and working memory; forms of cognitive control; neurocognitive aging; functional organization of prefrontal cortex, parietal cortex, and the medial temporal lobe; assessed by functional MRI, scalp and intracranial EEG, and transcranial magnetic stimulation."},{"lastName":"O'Hara","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor (Research),Psychiatry & Behavioral Science - Stanford/VA Aging Clinical Research Center"},{"appointment":"Member,Child Health Research Institute"}],"primaryAppointment":"Associate Professor (Research),Psychiatry & Behavioral Science - Stanford/VA Aging Clinical Research Center","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=5920&type=small&showNoImage","displayName":"Ruth O'Hara","firstName":"Ruth","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Ruth_O'Hara","researchInterest":"Dr. O\u0092Hara\u0092s research aims to identify physiological markers of neurocognitive impairment in a broad range of late-life disorders, including Mild Cognitive Impairment, Alzheimer\u0092s disease (AD), Late-Life Depression, and Late-Life Anxiety disorders."},{"lastName":"Giocomo","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Neurobiology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Assistant Professor,Neurobiology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=35065&type=small&showNoImage","displayName":"Lisa Giocomo","firstName":"Lisa","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Lisa_Giocomo","researchInterest":"My laboratory studies the cellular and molecular mechanisms underlying the organization of cortical circuits important for spatial navigation and memory. We are particularly focused on medial entorhinal cortex, where many neurons fire in spatially specific patterns and thus offer a measurable output for molecular manipulations. We combine electrophysiology, genetic approaches and behavioral paradigms to unravel the mechanisms and behavioral relevance of non-sensory cortical organization. Our fi"},{"lastName":"Goodkind","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Psychiatry & Behavioral Science"}],"primaryAppointment":"Postdoctoral Research fellow, Psychiatry & Behavioral Science","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=25070&type=small&showNoImage","displayName":"Madeleine Goodkind","firstName":"Madeleine","href":"http://med.stanford.edu/profiles/postdocs/researcher/Madeleine_Goodkind","researchInterest":""},{"lastName":"Polepalli","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Psychiatry & Behavioral Science"}],"primaryAppointment":"Postdoctoral Research fellow, Psychiatry & Behavioral Science","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=12891&type=small&showNoImage","displayName":"Jai Polepalli","firstName":"Jai","href":"http://med.stanford.edu/profiles/postdocs/researcher/Jai_Polepalli","researchInterest":""},{"lastName":"Luoma","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Neurosciences Institute"}],"primaryAppointment":"Postdoctoral Research fellow, Neurosciences Institute","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=24597&type=small&showNoImage","displayName":"Jessie Luoma","firstName":"Jessie","href":"http://med.stanford.edu/profiles/postdocs/researcher/Jessie_Luoma","researchInterest":""},{"lastName":"Madison","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Molecular & Cellular Physiology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Associate Professor,Molecular & Cellular Physiology","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=4321&type=small&showNoImage","displayName":"Daniel V. Madison","firstName":"Vernon","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Vernon_Madison","researchInterest":"Our laboratory uses electrophysiological techniques to study the mechanisms of synaptic transmission and plasticity in the mammalian hippocampus. One of the main focuses in the lab is in the study of synaptic long-term potentiation (LTP). LTP is the persistent increase in synaptic strength that occurs after a period of heavy activity in a synaptic connection. It is the most widely studied and compelling model for mechanisms underlying memory formation in the mammalian central nervous system."},{"lastName":"Sullivan","clinicalFocus":[],"appointments":[{"appointment":"Professor (Research),Psychiatry & Behavioral Science - Neurosciences"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor (Research),Psychiatry & Behavioral Science - Neurosciences","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=4158&type=small&showNoImage","displayName":"Edith Vioni Sullivan","firstName":"Edith","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Edith_Sullivan","researchInterest":"Application of magnetic resonance imaging modalities and component process analysis of cognitive, sensory, and motor functions to identify brain structural and functional mechanisms disrupted in neurodegenerative conditions:  alcoholism, Alzheimer's disease, HIV infection, and normal aging.  Our laboratory is applying structural MRI, MR spectroscopy, and MR diffusion tensor imaging to animal models of aging and alcoholism in parallel with the human studies."},{"lastName":"Aoto","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Neurosciences Institute"}],"primaryAppointment":"Postdoctoral Research fellow, Neurosciences Institute","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=14864&type=small&showNoImage","displayName":"Jason Aoto","firstName":"Jason","href":"http://med.stanford.edu/profiles/postdocs/researcher/Jason_Aoto","researchInterest":""},{"lastName":"Saggar","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Psychiatry & Behavioral Science"}],"primaryAppointment":"Postdoctoral Research fellow, Psychiatry & Behavioral Science","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=23965&type=small&showNoImage","displayName":"Manish Saggar","firstName":"Manish","href":"http://med.stanford.edu/profiles/postdocs/researcher/Manish_Saggar","researchInterest":""},{"lastName":"Palmer","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Neurosurgery"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Associate Professor,Neurosurgery","imageUrl":"http://stanfordhospital.org/profiles/viewImage?facultyId=5930&type=small&showNoImage","displayName":"Theo Palmer","firstName":"Theo","href":"http://med.stanford.edu/profiles/stanfordhospital/researcher/Theo_Palmer","researchInterest":"For most areas of the mammalian brain, the production of new nerve cells or neurons is restricted to fetal development. However, there are exceptions to the rule. Some areas of the brain continue to make new neurons throughout life. This neurogenesis is mediated by neural stem cells and our research goals are to understand how stem cell activity and fate are controlled. Ultimately, we hope to harness the nascent potential of stem cells to treat neurological injury and disease."}]}