Jean Y. Tang MD PhD
Publication Details
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Targeting superficial or nodular Basal cell carcinoma with topically formulated small molecule inhibitor of smoothened.
Clin Cancer Res. 2011; (10): 3378-87
Inappropriate activation of the Hedgehog (Hh) signaling pathway in skin is critical for the development of basal cell carcinomas (BCC). We have investigated the anti-BCC efficacy of topically-applied CUR61414, an inhibitor of the Hh signal transduction molecule Smoothened.
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