Athena Cherry

Publication Details

  • A Pediatric B Lineage Leukemia With Coincident MYC and MLL Translocations JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY Meeker, N. D., Cherry, A. M., Bangs, C. D., Frazer, J. K. 2011; 33 (2): 158-160

    Abstract:

    Translocations are key oncogenic events, and many rearrangements are characteristic for a specific malignancy. We present here a case of phenotypic precursor-B acute lymphoblastic leukemia (ALL), subsequently found to have both MYC and MLL translocations. Owing to the potential prognostic impact of these translocations, a novel treatment strategy was applied which merged precursor-B ALL, Burkitt-ALL, and "MLL-adapted" rationales. With the advent of expanding diagnostic panels and molecular therapeutic options, use of such adapted therapies for individualized treatment will undoubtedly continue to increase as we move toward pharmacogenomic-based approaches.

    View details for DOI 10.1097/MPH.0b013e3181e65c39

    View details for Web of Science ID 000287648800031

    View details for PubMedID 20829716

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