Josef Parvizi

Publication Details

  • Electrical stimulation of the human brain: perceptual and behavioral phenomena reported in the old and new literature FRONTIERS IN HUMAN NEUROSCIENCE Selimbeyoglu, A., Parvizi, J. 2010; 4

    Abstract:

    In this review, we summarize the subjective experiential phenomena and behavioral changes that are caused by electrical stimulation of the cerebral cortex or subcortical nuclei in awake and conscious human subjects. Our comprehensive review contains a detailed summary of the data obtained from electrical brain stimulation (EBS) in humans in the last 100 years. Findings from the EBS studies may provide an additional layer of information about the neural correlates of cognition and behavior in healthy human subjects, or the neuroanatomy of illusions and hallucinations in patients with psychosis and the brain symptomatogenic zones in patients with epilepsy. We discuss some fundamental concepts, issues, and remaining questions that have defined the field of EBS, and review the current state of knowledge about the mechanism of action of EBS suggesting that the modulation of activity within a localized, but distributed, neuroanatomical network might explain the perceptual and behavioral phenomena that are reported during focal electrical stimulation of the human brain.

    View details for DOI 10.3389/fnhum.2010.00046

    View details for Web of Science ID 000282826500001

    View details for PubMedID 20577584

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