Christian Guilleminault

Publication Details

  • Surgical Options for the Treatment of Obstructive Sleep Apnea MEDICAL CLINICS OF NORTH AMERICA Holty, J. C., Guilleminault, C. 2010; 94 (3): 479-?

    Abstract:

    Obstructive sleep apnea (OSA) is a prevalent condition characterized by repetitive airway obstruction during sleep with associated increased morbidity and mortality. Although CPAP is the preferred treatment, poor compliance is common. Patients intolerant of conventional OSA medical treatment may benefit from surgical therapy to alleviate pharyngeal obstruction. Case series suggest that maxillomandibular advancement has the highest surgical efficacy (86%) and cure rate (43%). Soft palate surgical techniques are less successful, with uvulopalatopharyngoplasty having an OSA surgical success rate of 50% and cure rate of 16%. Further research is needed to more thoroughly assess clinical outcomes (eg, quality of life, morbidity), better identify key preoperative patient and clinical characteristics that predict success, and confirm long-term effectiveness of surgical modalities to treat OSA.

    View details for DOI 10.1016/j.mcna.2010.02.001

    View details for Web of Science ID 000278853600005

    View details for PubMedID 20451028

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