Daniel A. Arber, M.D.

Publication Details

  • CD20-positive peripheral T-cell lymphoma: Report of a case after nodular sclerosis Hodgkin's disease and review of the literature MODERN PATHOLOGY Mohrmann, R. L., Arber, D. A. 2000; 13 (11): 1244-1252


    We present a case of peripheral T-cell lymphoma co-expressing CD3 and CD20, as well as demonstrating T-cell receptor gene rearrangement, in a patient who had been diagnosed with nodular sclerosis Hodgkin's disease 5 years previously. Although 15 cases of CD20-positive T-cell neoplasms have been previously reported in the literature, this is the first report of CD20-positive T-cell lymphoma occurring subsequent to treatment of Hodgkin's disease. The current case affords an opportunity to review the rarely reported expression of CD20 in T-cell neoplasms as well as the relationship between Hodgkin's disease and subsequently occurring non-Hodgkin's lymphomas. In addition, the identification of this case supports the suggestion that the use of CD20 antibodies alone in paraffin sections may lead to an incorrect determination of cell lineage in some cases.

    View details for Web of Science ID 000165570500013

    View details for PubMedID 11106083

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