Robert Herfkens

Publication Details

  • Dynamic breast MRI with spiral trajectories: 3D versus 2D JOURNAL OF MAGNETIC RESONANCE IMAGING Yen, Y. F., Han, K. F., Daniel, B. L., Heiss, S., Birdwell, R. L., Herfkens, R. J., Sawyer-Glover, A. M., Glover, G. H. 2000; 11 (4): 351-359

    Abstract:

    A three-dimensional (3)D spiral sequence was developed for dynamic breast magnetic resonance (MR) imaging with much improved image quality. Partial Z phase encoding was applied to obtain thinner slices for a coverage of the whole breast. Comparison between the 3D and a previously developed multi-slice 2D spiral sequences was performed on ten healthy volunteers without contrast and five breast patients with gadolinium-diethylene triamine pentaacetic acid (Gd-DTPA). The 3D spiral images had significantly less off-resonance blurring and spiral artifacts. With a small compromise on temporal resolution (7.7 seconds in 2D and 10.6 seconds in 3D), we obtained 32 interpolated 3-5 mm slices (with 20 Z phase encodes) for a full coverage of 10-16 cm breast with the same 1 x 1 mm2 in-plane resolution as the 2D sequence, which had 12 8-13 mm slices. Contrast between glandular and soft tissue in normal breasts was increased by about 25%. The reduced repetition time in the 3D spiral acquisition led to an increased Gd-enhanced signal. The difference between the enhancement of malignant and benign lesions increased by sevenfold. We expect that this new development could lead to improved specificity in characterizing breast lesions using MR imaging.

    View details for Web of Science ID 000087572700002

    View details for PubMedID 10767063

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