Steven Artandi

Publication Details

  • Telomerase flies the coop: the telomerase RNA component as a viral-encoded oncogene JOURNAL OF EXPERIMENTAL MEDICINE Artandi, S. E. 2006; 203 (5): 1143-1145

    Abstract:

    Telomerase, the enzyme that elongates our telomeres, is crucial for cancer development based on extensive analyses of human cells, human cancers, and mouse models. New data now suggest that a viral telomerase RNA gene encoded by Marek's disease virus (MDV), an oncogenic herpesvirus of chickens, promotes tumor formation. These findings highlight the importance of telomerase in cancer and raise new questions regarding the mechanisms by which the telomerase RNA component supports tumorigenesis.

    View details for DOI 10.1084/jem.20060849

    View details for Web of Science ID 000237803700003

    View details for PubMedID 16682501

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