Lawrence Steinman

Publication Details

  • A neuropeptide in immune-mediated inflammation, Y? TRENDS IN IMMUNOLOGY Prod'homme, T., Weber, M. S., Steinman, L., Zamvil, S. S. 2006; 27 (4): 164-167

    Abstract:

    Disturbances in crosstalk between the immune system and the sympathetic nervous system (SNS) can contribute to the pathogenesis of Th1-mediated autoimmunity. Recent studies indicate that neuropeptide Y (NPY) has a major role in the regulation of Th1 responses. The precise role of NPY has been an enigma, but a recent study provides a breakthrough, demonstrating that NPY has a bimodal role as a negative regulator of T cells and an activator of antigen-presenting cell function.

    View details for DOI 10.1016/J.IT.2006.02.003

    View details for Web of Science ID 000237145700002

    View details for PubMedID 16530483

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