Mark Holodniy

Publication Details

  • Utilization and access to Antiretroviral genotypic resistance testing and results within the US department of veterans affairs JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES Goetz, M. B., Holodniy, M., Poulton, J. S., Rodriguez, F. H., Rigsby, M. O. 2006; 41 (1): 59-62


    We sought to characterize variation in the use of HIV genotypic resistance tests and how results were reported.Clinicians and laboratory managers at all Veterans Affairs (VA) medical centers were asked to complete a survey in March 2003 regarding HIV resistance testing practices.Surveys from 131 of 150 sites were returned. Forty-eight percent of HIV clinicians indicated that US Department of Health and Human Services guidelines were the usual basis for ordering tests. Although between 12% and 31% of respondents indicated that they always, sometimes, seldom, or never ordered resistance tests in patients with acute or chronic HIV infection, >70% ordered tests in adherent patients with treatment failure. Among the 32 centers with >200 patients in care, 13 +/- 8 (mean +/- standard deviation) tests were performed per 100 patients in care during 2002. Forty-nine percent of clinicians said that tests were helpful, but only 33% expressed confidence in using test results. Only 40% of sites entered results in the VA electronic medical record.Ordering patterns for HIV resistance tests differed significantly among VA sites. A minority of clinicians indicated confidence in the use of test results. A consistent system to capture and present complete results was absent.

    View details for Web of Science ID 000234438500009

    View details for PubMedID 16340474

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