Upinder Singh

Publication Details

  • Genomic DNA microarrays for Entamoeba histolytica: Applications for use in expression profiling and strain genotyping EXPERIMENTAL PARASITOLOGY Macfarlane, R., Bhattacharya, D., Singh, U. 2005; 110 (3): 196-202


    The parasite Entamoeba histolytica is a causative agent of dysentery and liver abscesses. Found predominantly in developing countries, this parasitic infection is responsible for significant morbidity and mortality. We have developed a genomic DNA microarray for E. histolytica. The array composed of 11,328 clones contains >2000 unique genes and was utilized for expression profiling and comparative genomic hybridizations of Entamoeba strains. We present a synopsis of our results to date and potential future applications of microarray technology for the study of Entamoeba biology.

    View details for DOI 10.1016/j.exppara.2005.03.006

    View details for Web of Science ID 000230067400007

    View details for PubMedID 15955312

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