Kiran Kaur Khush, MD

Publication Details

  • Age and aneurysm position predict patterns of left ventricular dysfunction after subarachnoid hemorrhage JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY Khush, K., Kopelnik, A., Tung, P., Banki, N., Dae, M., Lawton, M., Smith, W., Drew, B., Foster, E., Zaroff, J. 2005; 18 (2): 168-174

    Abstract:

    Cardiac injury, including left ventricular dysfunction, frequently occurs in patients with subarachnoid hemorrhage. Patterns of left ventricular dysfunction often do not follow coronary artery distributions, and may correlate with myocardial sympathetic innervation. Left ventricular dysfunction of the anterior and anteroseptal walls that spares the apex is unusual for patients with myocardial infarction and may represent a neurally mediated pattern of injury. We performed serial echocardiography on 225 patients with subarachnoid hemorrhage and classified those with regional wall-motion abnormalities as following either an apex-sparing (AS) or apex-affected (AA) pattern. Wall-motion abnormalities were found in 61 of 225 patients studied (27%). The AS pattern was found in 49% of these patients. Younger age and anterior aneurysm position were independent predictors of this AS pattern. Both patterns of wall-motion abnormalities appear to be transient, reversible phenomena. The AS pattern may represent a unique form of neurally mediated cardiac injury.

    View details for DOI 10.1016/j.echo.2004.08.045

    View details for Web of Science ID 000226972000011

    View details for PubMedID 15682055

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