Andrew Quon

Publication Details

  • Comparison between 2-deoxy-2-[F-18]fluoro-D-Glucose positron emission tomography and positron emission tomography/computed tomography hardware fusion for staging of patients with lymphoma MOLECULAR IMAGING AND BIOLOGY Allen-Auerbach, M., Quon, A., Weber, W. A., Obrzut, S., Crawford, T., Silverman, D. H., Ratib, O., Phelps, M. E., Czernin, J. 2004; 6 (6): 411-416

    Abstract:

    2-Deoxy-2-[18F]fluoro-D-Glucose positron emission tomography (FDG-PET) stages patients with Hodgkin's disease (HD) and Non-Hodgkin's lymphoma (NHL) with higher accuracy than computed tomography (CT). We sought to determine whether integrated (hardware) fused PET/CT imaging results in further improvements in staging accuracy.Seventy-three patients (age 51 +/- 17 years, 37 female, 36 male) with HD (n = 20) or NHL (n = 53) undergoing staging were studied with an integrated PET/CT system. Image findings were verified by clinical follow up, additional imaging and when available, histology.Thirty-four of 73 patients (46.5%) had evidence of disease and 39 were disease free as confirmed by clinical evaluation and follow-up for 41 +/- 22 weeks (n = 73), including biopsy (n = 26), and other imaging modalities (n = 52) when available. A discordant image interpretation between PET and PET/CT occurred in seven patients (10%). PET/CT correctly upstaged two and downstaged five patients. Overall staging was accurate in 93% with PET/CT and 84% with PET (P = 0.03).Lymphoma is staged with higher accuracy using PET/CT than PET alone.

    View details for DOI 10.1016/j.mibio.2004.08.004

    View details for Web of Science ID 000225774500007

    View details for PubMedID 15564152

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