Peter J. Koltai MD, FACS, FAAP

Publication Details

  • Familial occurrence of acinic cell carcinoma of the parotid gland ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE Depowski, P. L., Setzen, G., Chui, A., Koltai, P. J., Dollar, J., Ross, J. S. 1999; 123 (11): 1118-1120


    We report the familial occurrence of acinic cell carcinoma involving the parotid gland, the first such report of which we are aware. The familial occurrence of any salivary gland neoplasm is rare. Several reports are present in the literature, including pleomorphic adenoma, Warthin tumor, carcinoma of the submandibular gland, and malignant lymphoepithelial lesion. We report the case of a 35-year-old man who underwent excision of a left parotid gland acinic cell carcinoma. Eight years later, his daughter presented at the age of 16 years with a nontender parotid gland mass that was excised and found also to be acinic cell carcinoma. The histologic features of both neoplasms were typical of acinic cell carcinoma. While this may represent a coincidental event, the possibility that this familial occurrence is a manifestation of common genetic or environmental risk cannot be excluded.

    View details for Web of Science ID 000083584000031

    View details for PubMedID 10539921

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