Steven Shafer
Publication Details
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Propofol dosing regimens for ICU sedation based upon an integrated pharmacokinetic-pharmacodynamic model.
Anesthesiology. 2001; (2): 324-33
The pharmacology of propofol infusions administered for long-term sedation of intensive care unit (ICU) patients has not been fully characterized. The aim of the study was to develop propofol dosing guidelines for ICU sedation based on an integrated pharmacokinetic-pharmacodynamic model of propofol infusions in ICU patients.
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