Darrell Wilson

Publication Details

  • Is growth hormone stimulation testing in children still appropriate? GROWTH HORMONE & IGF RESEARCH Gandrud, L. M., Wilson, D. M. 2004; 14 (3): 185-194

    Abstract:

    The diagnosis of growth hormone deficiency (GHD) historically has relied on measurement of growth hormone (GH) concentrations following stimulation, usually with a non-physiologic provocative agent. Despite the use of more specific GH assays, the peak concentration of GH below which a child is considered GH deficient has risen. We examine the pitfalls associated with GH stimulation tests, specifically, the lack of reliability and accuracy of these tests, and their inability to predict who will benefit from GH therapy. We recommend that GH stimulation tests no longer routinely be used for the diagnosis of GHD in children.

    View details for DOI 10.1016/j.ghir.2003.11.003

    View details for Web of Science ID 000221740100001

    View details for PubMedID 15125879

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