William Robinson

Publication Details

  • Genomic and proteomic analysis of multiple sclerosis - Opinion CURRENT OPINION IN IMMUNOLOGY Robinson, W. H., Utz, P. J., Steinman, L. 2003; 15 (6): 660-667


    Multiple sclerosis (MS) and other autoimmune diseases result from the dysregulation of genetic and proteomic programs. In MS, the loss of immune homeostasis leads to aberrant targeting and destruction of the myelin sheath, which manifests as the clinical syndrome of MS. The advent of technologies to perform large-scale analysis of mRNA transcript and protein expression will transform our understanding of the mechanisms underlying the initiation and progression of MS, and will yield new targets for therapeutic intervention.

    View details for DOI 10.1016/j.coi.2003.09.015

    View details for Web of Science ID 000186862400011

    View details for PubMedID 14630200

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