Donald Olson

Publication Details

  • Electroencephalography in holoprosencephaly: findings in children without epilepsy CLINICAL NEUROPHYSIOLOGY Hahn, J. S., Delgado, M. R., Clegg, N. J., Sparagana, S. P., Gerace, K. L., Barkovich, A. J., Olson, D. M. 2003; 114 (10): 1908-1917


    To evaluate the electroencephalographic characteristics of patients with holoprosencephaly (HPE) without epilepsy.We evaluated the electroencephalograms (EEGs) of 18 children with HPE who lacked a history of seizures. Neuroimaging studies were assessed for severity of HPE and thalamic non-separation and the presence of dorsal cysts and cortical malformations.Hypersynchronous theta activity occurred in 50 and 60% of EEGs during wakefulness or drowsiness/sleep, respectively, and correlated with the grade of thalamic non-separation (p<0.05). Hypersynchronous beta activity during sleep occurred in 41% of EEGs. Posterior amplitude attenuation occurred in 33% of EEGs and correlated with the presence of a dorsal cyst (p

    View details for DOI 10.1016/S1388-2457(03)00169-X

    View details for Web of Science ID 000185982300016

    View details for PubMedID 14499753

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