Sandra Luna-Fineman

Publication Details

  • HUMAN CYTOTOXIC LYMPHOCYTES-T SPECIFIC FOR AUTOLOGOUS FOLLICULAR LYMPHOMA RECOGNIZE IMMUNOGLOBULIN IN A MAJOR HISTOCOMPATIBILITY COMPLEX RESTRICTED FASHION CANCER LUNAFINEMAN, S., Lee, J. E., WESLEY, P. K., CLAYBERGER, C., KRENSKY, A. M. 1992; 70 (8): 2181-2186

    Abstract:

    Previously, autologous Burkitt lymphoma-specific cytotoxic T-lymphocytes (CTL) were found to express the gamma and delta T-cell receptor and recognize tumor idiotype in a major histocompatibility complex (MHC) unrestricted fashion.In this study, the authors established autologous CTL lines and clones specific for a B-cell follicular lymphoma.These CTL are tumor specific and inhibited by antiimmunoglobulin monoclonal antibodies, but unlike the Burkitt lymphoma-specific CTL, they are MHC restricted and express the alpha and beta T-cell receptor.These studies suggest that different B-cell lymphomas can induce CTL of different phenotypes and MHC restriction.

    View details for Web of Science ID A1992JT85900027

    View details for PubMedID 1394049

Stanford Medicine Resources:

Footer Links: