David Liang, MD, PhD

Publication Details

  • Geometric distortions of the mitral valvular-ventricular complex in chronic ischemic mitral regurgitation. Circulation Tibayan, F. A., Rodriguez, F., Zasio, M. K., Bailey, L., Liang, D., Daughters, G. T., Langer, F., Ingels, N. B., Miller, D. C. 2003; 108: II116-21

    Abstract:

    Better understanding of the precise 3-dimensional geometric changes of the mitral valvular-ventricular complex in chronic ischemic mitral regurgitation (CIMR) is needed in order to devise better surgical repair techniques. We hypothesized that changes after inferior myocardial infarction would be different in hearts that developed CIMR compared with those that did not.Twenty-four sheep underwent coronary snare and marker placement (annulus, papillary muscles, and anterior and posterior leaflets). After 8 days, cinefluoroscopy provided 3-dimensional marker data, and snare occlusion of obtuse marginal branches created inferior myocardial infarction, including the posterior papillary muscle. After 7 weeks, the 16 surviving animals were studied again and grouped by mitral regurgitation grade (>or= 2+, n=10 versus

    View details for PubMedID 12970219

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