David A. Relman

Publication Details

  • Lethal invasive cestodiasis in immunosuppressed patients JOURNAL OF INFECTIOUS DISEASES Olson, P. D., Yoder, K., Fajardo, L. F., Marty, A. M., van de Pas, S., Olivier, C., Relman, D. A. 2003; 187 (12): 1962-1966


    Using both traditional methods and broad-range 18S ribosomal DNA (rDNA) polymerase chain reaction, we examined 2 cases of lethal cestodiasis, in which the disease agent had been poorly identified or misidentified. In one case, involving a patient with AIDS, we identified the human dwarf tapeworm, Hymenolepis nana, as a cause of aberrant metastatic larval disease. In the second case with similar pathologic abnormalities, involving a patient with Hodgkin disease, we identified a larval cestode with a previously uncharacterized 18S rDNA sequence. A prior report of this case nearly 30 years ago, based on tissue examination, had suggested that the parasite was a sparganum.

    View details for Web of Science ID 000183722600017

    View details for PubMedID 12792874

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